MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif) ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of inflammation, where it attracts or enhances the expression of other inflammatory ...

The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family.

许多研究已经阐明了单核细胞在不同的自身免疫性疾病中募集的分子基础，其结论指出单核细胞趋化蛋白1（mcp-1），也即ccl2及其细胞表面受体ccr2起主要作用。

Monocyte chemoattractant protein-1 (MCP-1/CCL2) is one of the key chemokines that regulate migration and infiltration of monocytes/macrophages. Both CCL2 and its receptor CCR2 have been demonstrated to be induced and involved in various diseases.

mcp-1（单核细胞趋化蛋白-1），也称为趋化因子（cc 基序）配体 2 (ccl2)，属于 cc 趋化因子家族。 它在炎症过程中起着至关重要的作用，它吸引或增强其他炎症因子/细胞的表达。

2009年5月1日 · Monocyte chemoattractant protein-1 (MCP-1) is a potent chemoattractant for monocytes and macrophages to areas of inflammation. MCP-1 is a prototypical chemokine subject to coordinated regulation by immunomodulatory agents.

mcp-1 也是一种具有高诊断效果的生物标志物，可以 反映出mtb 感染不同阶段的差异。它也可以通过外 周血中mcp-1 的表达水平诊断和鉴别潜伏性肺结核。 4 mcp-1 在脑部疾病中的作用 mcp-1 可见于ad 的老年斑块和反应性小胶质细 胞中。mci 和轻度ad 患者的血清mcp-1 水平 ...

MCP-1 neutralizing Ab (CNTO888) treatment delays tumor growth in an in vivo xenograft mouse model of prostate cancer and inhibits the dissemination of estrogen-dependent breast cancer induced by macrophages in a zebrafish model .

Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively studied CC chemokine, and the amount of studies on its role in the etiologies of obesity- and diabetes-related diseases have increased exponentially during the past two decades. This review attempted to provide a …

MCP-1 (monocyte chemoattractant protein 1, also called CC-chemokine ligand 2) is a CC family chemokine that mobilizes monocytes from the bone marrow and attracts them to sites of inflammation 10 including the atherogenic arterial wall. 11–14 Μice lacking MCP-1 or its receptor CCR2 (CC-chemokine receptor 2) are protected from atherosclerosis ...