2024年5月20日 · Multidrug-resistant TB (MDR-TB) is a form of TB disease caused by a strain of M. tuberculosis complex that is resistant to rifampicin and isoniazid. Globally, an estimated 410 000 people (95% UI: 370 000–450 000) developed multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB) in 2022.

2023年12月21日 · Multidrug-resistant TB disease (MDR TB) is caused by germs that are resistant to two or more of the main TB medicines: isoniazid and rifampin. Two more serious forms of MDR TB are called pre-extensively drug-resistant TB (pre-XDR TB) …

耐多药结核病（MDR-TB）是一种 由对利福平和异烟肼具有耐药性的结核分枝杆菌复合群菌株引起的结核病。 2022年，全球估计有41万人（95%置信区间：37万 - 45万）患有耐多药结核病或利福平耐药结核病。 被诊断为耐多药/利福平耐药结核病患者的治疗成功率稳步提高，但仍然低得惊人。 2020年，全球治疗成功率为63%，比2019年的60%和2012年的50%有所上升。 耐多药/利福平耐药结核病持续发生和蔓延的两个原因是结核病治疗管理不善和人际传播。 大多数结核病患 …

目前，耐多药结核病（multidrug-resistant tuberculosis，MDR-TB）和利福平耐药结核病（Rifampicin-resistant tuberculosis，RR-TB）仍然是全球结核病控制工作所面临的严峻问题。 据世界卫生组织（World Health Organization，WHO）估算，2017年全球RR-TB新发病例55.8万例，其中MDR-TB 46万例，而其治疗成功率仅为54%，病死率达16% [1]。 我国也是MDR-TB和RR-TB高负担国家之一，MDR-TB和RR-TB的疫情非常严重 [1]。

WHO发表了首次全球范围内多重耐药结核菌（MDR-TB）感染的总体评估，调查显示，2004年全球MDR-TB感染患者估计共424203例，9个独立变量可能与结核菌多重耐药相关。[J Infect Dis 2006,194(4):479]

2025年1月6日 · Multidrug-resistant TB (MDR TB) disease is caused by TB bacteria that are resistant to at least isoniazid and rifampin, the most effective first-line TB treatment drugs. Isoniazid, rifampin, and a second-line injectable (amikacin, capreomycin, and kanamycin). Isoniazid, rifampin, a fluoroquinolone, and bedaquiline or linezolid.

Fig. 2.4.2 Number of people diagnosed with MDR/RR-TB (blue) and enrolled on treatment for MDR/RR-TB (red), 2010–2022, 30 high MDR/RR-TB burden countries Globally, the cumulative total number of people reported as enrolled on treatment for MDR/RR-TB from 2018 to 2022 was 824 988, only 55% of the 5-year target (2018–2022) of 1.5 million that ...

2024年3月24日 · Multidrug-resistant or rifampicin-resistant TB (MDR/RR-TB; resistance to rifampicin and isoniazid, or rifampicin alone) is a burgeoning public health challenge in several parts of...

Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs): isoniazid and rifampicin.

People with drug-resistant TB disease must be treated with medicines that can kill the TB germs. If you have drug-resistant TB disease, your health care provider will recommend a treatment plan for your specific type of drug-resistant TB disease. A treatment plan (also called treatment regimen) for drug-resistant TB disease is a schedule to ...