mLIF 在体外可诱导M1髓系白血病细胞的正常分化,并能够通过抑制小鼠胚胎干细胞(mouse embryonic stem cells, mESCs)的分化来维持 mESCs 的自我更新及多能性。 该产品为白色冻干粉末。 冻干前,溶于含 0.1% BSA 的D-PBS中,并使用0.22 μm 的微膜过滤除菌。 通过 SDS-PAGE 检测,纯度 > 95%。 每1 μg 蛋白中内毒素含量低于 0.1 ng;支原体阴性。 生物活性:通过诱导小鼠M1髓系白血病细胞分化检测,其生物活性 ≥ 1x108 活性单位/mg。 小鼠胚胎干细胞培养:1000 活性单 …

mLIF (recombinant mouse leukemia inhibitory factor) Cat.: L00100G Quantity: 1mL Description: Leukemia inhibitory factor (LIF) is a member of Interleukin 6 family. This protein is mainly expressed in the trophectoderm of the developing embryo, with its receptor LIFR expressed throughout the inner cell mass.

产品来源：mLIF 是使用 pGEX 表达系统在大肠埃希菌中表达的带 GST 的融合蛋白，用凝血酶从 GST 部分裂解，并通过多个 FPLC 步骤进行纯化。 白血病抑制因子（LIF）是一种淋巴样因子，可通过抑制自发分化来促进胚胎干细胞的长期维持。 LIF 具有许多其他活性，包括胆碱能神经元分化、干细胞多能性控制、骨骼和脂肪代谢、某些因子依赖性细胞系的有丝分裂，以及在体内对巨核细胞生成的促进。 小鼠LIF是一个22 kDa的蛋白质，含有 203 个氨基酸残基。 1.使用体外半固 …

2025年3月5日 · The identification of novel molecular candidates capable of treating osteoarthritis (OA) has significant clinical implications. Monocyte locomotion inhibitory factor peptide (MLIF) is a pentapeptide derived from Entamoeba histolytica. It has been found possesses selective anti-inflammatory effects both in vitro and in vivo.

Monocyte locomotion inhibitory factor peptide (MLIF) is a pentapeptide derived from Entamoeba histolytica. It has been found possesses selective anti-inflammatory effects both in vitro and in vivo. Nonetheless, like many peptide therapeutics, MLIF has relatively poor proteolytic stability and short half-life in vivo, hindering its effective ...

Our previous study found that MLIF protects against ischemic stroke in rats and mice and exerts a neuroprotection effect in human neuroblastoma SH-SY5Y cells. Microglia/macrophage polarization has been proven to be vital in the pathology of ischemic stroke.

单核细胞迁移抑制因子(monocyte locomotion inhibitory factor,MLIF)是阿米巴原虫产生的具有抗炎作用的五肽。 体内、外研究发现,MLIF可以发挥抗炎和免疫保护作用,对类风湿关节炎、神经损伤、心肌缺血、脑缺血及痴呆具有良好的保护作用。

Monocyte locomotion inhibitory factor (MLIF) is a heat-stable pentapeptide from Entamoeba histolytica. Our previous study found that MLIF protects against ischemic stroke in rats and mice and exerts a neuroprotection effect in human neuroblastoma SH-SY5Y cells.

它的车身较轻，非常适合在城市中穿梭和高速行驶，但坐垫偏硬，长时间骑行会很累；190SS坐垫相比之下稍宽点，相比之下更舒适点，190SS更注重舒适性和实用性。 它的座椅较高，驾驶姿势较为直立，非常适合长途骑行，在非铺装路面上，CB190SS 略长的轴距和辐条轮毂使其具有一定优势； . 制动方面，CBF190TR 配备了单通道的 ABS 防抱死系统，只有前轮搭载 ABS；CB190SS 则只配备了前轮单碟卡钳的单碟 ABS 制动系统。 CBF190TR 采用了板轮与子午线真空轮胎的 …

Entamoeba histolytica in culture produces a pentapeptide (MQCNS). This oligopeptide inhibits the in vitro and in vivo locomotion of human monocytes, hence its denomination Monocyte Locomotion Inhibitory Factor (MLIF). The original isolated peptide and its synthetic construct display similar effects, …