2020年12月20日 · Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM) remodeling endopeptidases that have the capacity to degrade almost every component of the ECM. The degradation of the ECM is of great importance, since it is related to embryonic development and angiogenesis.

Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM) remodeling endopeptidases that have the capacity to degrade almost every component of the ECM. The degradation of the ECM is of great importance, since it is related to embryonic development and angiogenesis.

2020年5月15日 · Matrix metalloproteinases (MMPs) are zinc dependent proteolytic metalloenzyme. MMP-9 is one of the most complex forms of matrix metalloproteinases. MMP-9 has the ability to degrade the extracellular matrix (ECM) components and has important role in the pathophysiological functions.

2020年5月5日 · Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate substrates by enzymatic cleavage and, on the basis of their activities, have been demonstrated to play a role in ageing.

结论:脑脊液中MMP-9与MCP-1参与了HSE的病理生理过程,可以作为HSE的临床诊断与干预指标。 Objective:To investigate MMP-9 and MCP-1 levels in cerebrospinal fluid of patients with herpes simplex encephalitis, and to explore the clinical relationship.

2020年10月6日 · Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability. Studies have demonstrated that MMP-9 levels are higher in vulnerable plaques than in stable plaques.

2025年1月15日 · Matrix metalloproteinases (MMPs) control the complex processes of morphogenesis and tissue remodelling. They are important for both homeostatic and developmental processes, and play a role in regulation. The MMPs participants in the pathophysiology of many illnesses, such as ECM disruption and tissue remodelling caused by dysregulated MMP activity.

2020年10月6日 · Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability. Studies have demonstrated that MMP-9 levels are higher in vulnerable plaques than in stable plaques.

2020年6月27日 · Our study suggests that MMP-9 may be an early indicator of respiratory failure in COVID-19 patients and underscore the role ECM remodeling and fibrosis in this disorder. Treatment modalities targeting MMP-9 activity or neutrophil activation could be of importance in COVID-19 lung disease.

2020年5月15日 · MMP-9 is one of the most complex forms of matrix metalloproteinases. MMP-9 has the ability to degrade the extracellular matrix (ECM) components and has important role in the pathophysiological functions. Overexpression and dysregulation of MMP-9 is associated with various diseases.