2017年9月19日 · MBs proceed through promyelocytes (PMCs), metamyelocytes (MMs), and band cells (BCs) to become mature polymorphonuclear neutrophils (PMNs). Riffelmacher et al. (2017) took advantage of LC3-GFP transgenic autophagy reporter mice to monitor the autophagy activity in MBs, MCs, MMs, BCs, and PMNs. They found a dynamic change of autophagy activity ...

To understand the regulation of autophagy in normal neutrophil differentiation, we defined the five differentiation stages of myeloblasts (MBs), myelocytes (MCs), metamyelocytes (MMs), band cells (BCs), and neutrophils (PMNs) (Satake et al., 2012) and confirmed those stages by morphology on Wright-Giemsa-stained cytospins (Figures 1A, 1B, and ...

2025年2月13日 · In this study, we report the isolation and characterization of two new SSC hi CD66b - CD64 dim CD115 - NCPs that, by phenotypic, transcriptomic, maturation and immunohistochemistry properties, as...

2025年2月4日 · 1957 年，Bardeen、Cooper 和 Schrieffer（BCS）发表了第一个真正微观的超导理论。 该理论很快被公认为在本质上完全正确，并成功解释了许多重要的实验现象。 例如，该理论正确解释了 同位素效应： T_c \propto M^ {-\alpha} 其中转变温度 $T_c$ 随晶格离子的质量 $M$ 变化。 原始的 BCS 理论 预测同位素指数 $\alpha$ 为 $\frac12$。 大多数常见超导体与这一预测非常吻合，如下表所示。 然而，也有一些例外。 过渡金属如钼（$\text {Mo}$）和锇（$\text …

System specification document for the MMS project detailing alignment and coordinate systems. Includes ACS hardware, propulsion, and thruster information.

通过Bulk-RNA测序，对NCPs, HSC/MPPs ,CMPs, PMs, MYs, MMs, BCs, SNs, PMNs进行转录组特征分析（PCA分析）发现，NCPs 的转录水平位于CMPs和PMs之间，且NCPs各亚群之间相互聚集（A），其CD34和PTPRC（编码CD45）基因的转录水平也与 流式结果一致（B，C）为精确剖析NCPs转录组的异质性 ...

MBs proceed through promyelocyte (MC), metamyelocyte (MM), and band cell (BC) stages to become a mature polymorphonuclear neutrophil (PMN) (Bardoel et al., 2014). This process is characterized by striking remodeling of the nucleus and temporally regulated granule generation by timed synthesis, which clearly demarcates stages of differentiation.

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Abstract: The in vivo expression profiles of cell-cycle proteins regulating G1-to-S-phase transition were determined in three neutrophil precursor populations from human bone marrow: myelo-blasts (MBs) and promyelocytes (PMs); myelocytes (MCs) and metamyelocytes (MMs); and band cells (BCs) and segmented neutrophil cells (SCs) and in mature polym...

In vivo distribution of myeloid transcription factors during granulopoiesis was investigated by Northern and Western blotting in 3 neutrophil precursor populations from human bone marrow: immature...