In patients with GN or vasculitis, ANCAs are directed against proteinase 3 (PR3) or myeloperoxidase (MPO). The differences between PR3-ANCA-associated vasculitis (AAV) …

Concurrent testing for serum antineutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence (IF) and by anti-proteinase-3 (PR3)/anti-myeloperoxidase (MPO) …

2009年3月4日 · A remarkable lower survival rate was observed in ANCA-PR3-positive patients compared to ANCA-MPO-positive patients. We also demonstrated that patients characterized …

MPO-ANCA was predominant in Chinese patients with ANCA-associated vasculitis and renal disease. The epidemiological characteristics, extra-renal involvement, and histopathological …

2015年10月17日 · 不断有证据证明pr3-aav和mpo-aav是一个实体的两种截然不同的疾病，两者在病因、流行病学、遗传背景、临床表现等方面均存在差别。 建议通过ANCA血清型对患者进行 …

The differences between PR3-ANCA-associated vasculitis (AAV) and MPO-AAV described in the past have been supplemented during the last decade. In this review, we discuss the …

2022年6月1日 · PR3-ANCA had greater sensitivity than MPO-ANCA for GPA (74% vs 11%, p < 0.001) and MPO-ANCA greater sensitivity for MPA (73% vs 7%, p < 0.001). Specificities of …

After normalizing protein levels, we used unadjusted and age, sex, and steroid usage-adjusted linear regression to compare levels in MPO- vs PR3-ANCA+ AAV. Results: Of those with …

PR3-ANCA had greater sensitivity than MPO-ANCA for GPA (74% vs 11%, p < 0.001) and MPO-ANCA greater sensitivity for MPA (73% vs 7%, p < 0.001). Specificities of both MPO-ANCA …

2017年10月10日 · anca相关性血管炎是一种异质性疾病，其特点是anca阳性的小血管坏死性炎症。ancas可根据其靶抗原分类，包括蛋白酶3 (pr3) 和髓过氧化物酶 (mpo)。近来有学者认为， …