Use of gadolinium-based contrast agents (GBCA) in renal impairment is controversial, with physician and patient apprehension in acute kidney injury (AKI), chronic kidney disease (CKD), and dialysis because of concerns regarding nephrogenic systemic fibrosis (NSF).

2023年5月12日 · Kidney length and volume can be measured with anatomical MR images, typically T 2-weighted scans to measure total kidney volume (TKV) 4, 5 and T 1-weighted scans for segmentation of the cortex and medulla. 5 TKV is a key prognostic measure in persons with autosomal dominant polycystic kidney disease (ADPKD) but may also be important in ...

2025年3月11日 · Contrast agents are injected into a vein in the hand or arm. The contrast agents used for MRI scans often contain a chemical element called gadolinium (gad-oh-LIN-e-um). Newer contrast agents that contain gadolinium are generally safe for people with kidney disease, even those who receive dialysis.

2020年11月1日 · Contrast-induced acute kidney injury (CI-AKI) and nephrogenic systemic fibrosis (NSF) have been 2 of the most feared adverse effects of iodinated contrast media for computed tomography (CT) and gadolinium-based contrast media for …

2020年11月10日 · Depending on the clinical indication, the potential harms of delaying or withholding group II or group III GBCM for an MRI in a patient with acute kidney injury or eGFR less than 30 mL/min per 1.73 m 2 should be balanced against and may outweigh the risk of NSF.

Conventional MRI provides high-resolution images of the macroscopic structure of the kidneys, which may point toward possible causes of CKD (such as autosomal dominant polycystic kidney disease). The past two decades have witnessed the arrival of new MRI techniques that can quantify functional or microscopic properties of the kidneys, such as ...

2020年8月27日 · Gadolinium-based contrast agents (GBCAs) improve the diagnostic capabilities of magnetic resonance imaging. Although initially believed to be without major adverse effects, GBCA use in patients with severe chronic kidney disease (CKD) was demonstrated to cause nephrogenic systemic fibrosis (NSF).

Many pathological (functional and structural) changes or factors in renal disease can be assessed by advanced MRI techniques. These include renal vascular structure and function (contrast-enhanced MRI, arterial spin labeling), tissue oxygenation (blood oxygen level-dependent MRI), renal tissue injury and fibrosis (diffusion or magnetization ...

Imaging modalities for kidney evaluation include ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI). Each of these methods has unique advantages that must be considered in clinical practice. Ultrasound is non-invasive and widely available. It is often the first-line imaging technique used.

2025年2月21日 · These insults can lead to the development of chronic kidney disease (CKD) and acute kidney injury (AKI) . CKD is the third leading cause of diminished global life expectancy, posing a significant public health challenge worldwide . ... NBIC integrates advanced technologies such as high-field MRI, multiphoton optical microscopy, synchrotron ...

2023年4月13日 · Radiologists are most interested in the imaging implications for patients with stage 4 (eGFR < 30 mL/min per 1.73 m 2) and stage 5 (eGFR < 15 mL/min per 1.73 m 2) chronic kidney disease, with stage 5 considered kidney failure (2, 3).

2021年11月11日 · Magnetic resonance imaging (MRI) is playing an increasingly important role in evaluating chronic kidney disease (CKD). It has the potential to be used not only for...

2023年5月13日 · Recent advances in multiparametric magnetic resonance imaging (MRI) allow multiple quanti-tative measures to assess kidney morphology, tissue microstructure, oxygenation, kidney blood flow, and perfusion to be collected in a single scan session.

2 天之前 · Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J ... Percutaneous CT- and MRI-guided Cryoablation of cT1 Renal Cell Carcinoma: Intermediate- to Long-term Outcomes in 307 Patients. Radiology 2020;296(3) :687–695. Google Scholar. 37. Campbell SC, Clark PE, Chang SS, ...

2015年1月19日 · CT contrast materials do rarely cause kidney damage and a skin disorder called nephrogenic systemic fibrosis (NSF) can be caused by the MRI contrast agents. Patients with poor kidney function are the people at risk for these side effects. In this blog I will discuss the approach to these issues at UCSF.

2015年10月2日 · Diffusion MRI showed no differences between CKD and healthy controls. These data demonstrate that BOLD MRI can be used to identify enhanced hypoxia associated with CKD and the preliminary observations are consistent with the chronic hypoxia model for disease progression in CKD.

2015年10月2日 · These data demonstrate that BOLD MRI can be used to identify enhanced hypoxia associated with CKD and the preliminary observations are consistent with the chronic hypoxia model for disease progression in CKD. Longitudinal studies are warranted to further verify these findings and assess their predic …

2008年5月21日 · The use of contrast in patients with renal impairment: Choosing CT or MRI. The following points should be considered in deciding whether a contrast-enhanced CT or MRI examination should be performed in a patient with reduced renal function. 1) Patients at high risk should be identified before contrast administration.

Current methods to assess CKD (e.g. serum creatinine, albuminuria and ultrasound) are insensitive to early kidney damage, do not usually provide insight into the aetiology of underlying kidney disease and do not reliably allow individual patient stratification in terms of prognosis or therapy decisions.

Magnetic resonance imaging (MRI) of normal and diseased kidneys shows great promise because of the combined value of anatomical and functional information provided, as well as of specific contrast patterns that can be observed non-invasively. Multicontrast MRI is able to show infiltrative kidney dis …