2023年8月14日 · The presenting symptoms of patients are highly variable. Symptoms can include cognitive disturbance, visual changes, hemiparesis, ataxia, and sensory deficits. The UMN signs of MS are due to the demyelination of upper motor neurons. MRI is the imaging test of choice used to diagnose MS. CSF studies may also be used to aid in diagnosis.

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3.3. MRI. In addition to ruling out structural/inflammatory/infectious etiologies for UMN syndromes, quantitative MRI analysis has identified additional ways to potentially distinguish PLS from other UMN syndromes. Focal ‘knife edge’ atrophy of the precentral gyrus has typically been identified as the only structural abnormality allowed in PLS.

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An upper motor neuron lesion (also known as pyramidal insufficiency) Is an injury or abnormality that occurs in the neural pathway above the anterior horn cell of the spinal cord or motor nuclei of the cranial nerves.

2023年7月24日 · The imaging test of choice to diagnose MS is MRI. Intrathecal immunoglobulin G and oligoclonal bands are common findings in a cerebrospinal fluid analysis of an MS patient that can support the diagnosis.

运动神经元病 （Motor neuron disease，MND）是一类上、下运动神经元受累为主的致死的神经系统变性疾病。 纯上运动神经元-UMN和下运动神经元-LMN代表MND谱系的临床两端。 一. 肌萎缩侧索硬化 （amyotrophic lateral sclerosis，ALS） ALS是MND的经典类型，俗称 渐冻症，是一种累及上/下运动神经元及其支配的躯干、四肢和头面部肌肉的，一种慢性、进行性变性疾病，常表现为上/下运动神经元合并受损所致的进行性加重的肌无力、肌萎缩和肌束颤动等。 一般中老年发 …

2019年12月27日 · Amyotrophic lateral sclerosis (ALS) is clinically characterized by progressive dysfunction of upper motor neuron (UMN) and lower motor neuron (LMN).

2023年8月14日 · UMN lesions are designated as any damage to the motor neurons that reside above nuclei of cranial nerves or the anterior horn cells of the spinal cord. Damage to UMN’s leads to a characteristic set of clinical symptoms known as the upper motor neuron syndrome. These symptoms can include weakness, spasticity, clonus, and hyperreflexia.

2008年1月1日 · Diagnosis: CT or magnetic resonance imaging (MRI) of the brain; confirmation of diagnosis by biopsy. Treatment: Surgical only if symptomatic. Pathological clue: Suspect meningioma on the USMLE if a case is presented with increased intracranial pressure along with psammoma bodies on pathology report. Notes: 1.