Selected reaction monitoring (SRM), also called multiple reaction monitoring (MRM), is a method used in tandem mass spectrometry in which an ion of a particular mass is selected in the first stage of a tandem mass spectrometer and an ion product of a fragmentation reaction of the precursor ions is selected in the second mass spectrometer stage ...

MRM 是一种常用于 三重四极杆质谱 （Triple Quadrupole MS）的多重反应监测技术，适用于同时定量多个目标化合物。 它通过选择母离子和子离子对的反应进行监测，具有更高的选择性。

SRM, also known as multiple reaction monitoring (MRM), is an MS-based technique which can accurately measure the relative or absolute concentrations of particular molecules such as peptides/proteins, identified in proteomic profiling studies. You might find these chapters and articles relevant to this topic.

质谱多反应监测MRM蛋白鉴定技术作为一种高特异性、高灵敏度的质谱数据获取方式，在进行蛋白质组学更具针对性的研究中发挥了重要作用，受到很多研究者们的关注。

Selected Reaction Monitoring (SRM) is a targeted mass spectrometry technique primarily utilized for the quantification of specific analytes within a complex mixture. It involves isolating and monitoring predefined precursor-product ion transitions, enabling high selectivity and sensitivity.

An MRM data acquisition method contains settings such as compound names, ISTD (optional), MRM transitions, fragmentor voltages, and collision energies. With the MassHunter MRM/dMRM/tMRM Database, you can easily import all of these settings from the database to create an MRM method.

Key Parameters of Multiple Reaction Monitoring (MRM) • Dwell Time: Dwell time is the time spent acquiring a specific MRM transition during each cycle. A very short dwell times can be used (5 ms or less). However, longer dwell times are always desirable for better signal/noise and sensitivity,

Multiple reaction monitoring (MRM) profiling is a strategy for the exploratory analysis of small molecules and lipids by direct sample injection, ie, without the use of chromatographic separation. It is based on instrument methods that comprise a ...

Multiple reaction monitoring (MRM) is a mass spectrom- etry technique based on selection of a peptide ion and one or more characteristic fragment ions. The MRM method has previously been shown to be specific, accurate, and reproducible between laboratories.

New dynamic MRM methods on the Agilent 6400 Series triple quad instruments create new capability to tackle large multi-analyte assays and to accurately quantify exceedingly narrow peaks from fast Agilent 1200 Series RRLC and 1290 Infinity UHPLC separations.