Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4 ...
2007年9月2日 · We now demonstrate that mice lacking Mrp8-Mrp14 complexes are protected from endotoxin-induced lethal shock and Escherichia coli –induced abdominal sepsis. Both …
Multidrug resistance proteins (MRPs): Structure, function and …
2021年1月1日 · MRP8 has two TMDs, showing high homology with MRP5, another member of the multidrug resistant-associated protein family. MRP8 is highly expressed in breast cancer, …
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4 ...
We now demonstrate that mice lacking Mrp8-Mrp14 complexes are protected from endotoxin-induced lethal shock and Escherichia coli-induced abdominal sepsis. Both proteins are …
Ablation of Myeloid Cell MRP8 Ameliorates Nephrotoxic Serum
2020年2月20日 · In this study, Myeloid lineage cell-specific MRP8 knockout mice were generated, and nephrotoxic serum-induced glomerulonephritis was developed. Mice with conditional …
髓系相关蛋白（MRP）8和MRP14是S100家族的钙结合蛋白，是由 …
髓相关细胞（MRP）8和MRP14是在骨髓单核细胞中表达的S100家族的两个成员，它们具有某些细胞外功能，例如抗微生物，抑制细胞生长和趋化活性。 由于S100蛋白缺乏通过经典内质网/高 …
MRP8通过NF-κB信号通路调控痛风细胞模型中IL-1β的表达
摘要： 目的 研究髓样相关蛋白8(MRP8)在痛风中的作用及其机制。方法 单钠尿酸盐(MSU)结晶诱导巨噬细胞产生痛风模型,检测诱导后巨噬细胞中MRP8的水平。MRP8 siRNA转染巨噬细 …
人中性粒细胞中髓样相关蛋白 8 (MRP8) 和 MRP14 的亚细胞分布 …
骨髓相关蛋白 8 (MRP8) 和 MRP14 是 S100 家族钙结合蛋白，它们形成称为 MRP8/14 的异二聚体，存在于中性粒细胞和单核细胞的细胞质中。 MRP8/14 与单核细胞和中性粒细胞粘附和迁移 …
The subcellular distribution of myeloid-related protein 8 (MRP8…
2005年9月28日 · Myeloid-related protein 8 (MRP8) and MRP14 are S100 family calcium binding proteins that form a heterodimer known as calprotectin or MRP8/14 that is present in the …
The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the ...
2010年5月9日 · Myeloid-related protein-8 (Mrp8) and Mrp14 are damage-associated molecular pattern molecules (DAMPs) highly upregulated in various autoimmune disorders. We show in …
Myeloid-related Protein (MRP) 8 and MRP14, Calcium
1997年4月4日 · Release of MRP8 and MRP14 is associated with down-regulation of their de novo synthesis, suggesting that extracellular signaling via MRP8/MRP14 is restricted to distinct …