Artesunate inhibits cell proliferation and decreases growth hormone ...
2012年1月5日 · To determine the effect of artesunate (ART) on the rat pituitary adenoma GH3 cell line to evaluate its potential as a novel agent in growth hormone (GH) adenoma and to …
Effects of octreotide on autophagy markers and cell viability …
2020年1月29日 · We used the reduction of the tetrazolium salt 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) as a marker of redox activity in GH3 cells incubated for …
垂体腺瘤研究的常用工具：细胞系和原代细胞。,Pituitary - X-MOL
发现2014年1月至2019年7月发表的文章中常用的细胞系是GH3，AtT20，MMQ，GH4C1，HP75和TtT / GF。 此外，令人高兴的是，已经使用了许多方 …
Inhibitory effect of leptin on growth hormone secretion of GH3 …
2009年5月1日 · The results of MTT cell proliferation assay showed that leptin inhibited significantly the proliferation of GH3 cells in a dose-dependent manner (Fig. 3) (P < 0.05). We …
Grifolic acid induces GH3 adenoma cell death by inhibiting ATP ...
GH3 cells, the rat anterior pituitary adenoma cells, were cultured and the cell death was measured by MTT assay and Annexin V/PI staining. The mitochondrial membrane potential (MMP) of …
Both estrogen receptor α and β stimulate pituitary GH gene
Somatotroph GH3 and MtT/S cells were used as in vitro models. … Although sex steroids have been implicated in the control of mammalian growth, their direct effect on GH synthesis is less …
Nitric oxide mediates apoptosis and mitochondrial dysfunction …
2017年12月6日 · In the present study, the results of MTT assay displayed a concentration- and time-dependent decrease in cell viability induced by NIV in rat pituitary GH3 cells (Fig. 1A). …
雌激素受体拮抗剂对垂体腺瘤GH3细胞增殖、凋亡、催乳素分泌及 …
目的 通过检测雌激素受体拮抗剂对垂体腺瘤GH3细胞增殖、凋亡、催乳素 (PRL)分泌及雌激素受体蛋白表达的影响,探讨雌激素在垂体催乳素腺瘤发生、发展中的作用机制.方法 对去激素培养条 …
p38MAPK通路特异性抑制剂SB203580对大鼠垂体GH3细胞增殖和 …
结果 sb203580能够有效抑制生长激素腺瘤gh3细胞的增殖（p <0.05）,并呈现良好的时间依赖性与浓度依赖性。不同浓度的sb203580能够显著诱导生长激素腺瘤gh3细胞凋亡（p <0.05）。
A transforming growth factor-alpha pathway is expressed in ... - PubMed
We examined expression of TGF alpha in three related clones of pituitary tumor cells (GH1, GH3, and GH4C1) grown as transplantable tumors, the MtT/W5 tumor from which they were …