MUTYH (mutY DNA glycosylase) is a human gene that encodes a DNA glycosylase, MUTYH glycosylase. It is involved in oxidative DNA damage repair and is part of the base excision …

2023年7月17日 · What does a MUTYH mutation mean for my blood relatives? If you have a mutation in 1 of your MUTYH genes, your biological parents, siblings, and children each have …

2024年12月25日 · MUTYH (MutY DNA Glycosylase) is a Protein Coding gene. Diseases associated with MUTYH include Familial Adenomatous Polyposis 2 and Gastric Cancer. …

If you have MUTYH-associated polyposis, you inherited a mutation (change) in your MUTYH gene. This gene mutation raises your risk of certain cancers, especially colorectal cancer. …

2012年10月4日 · MUTYH polyposis (also referred to as MUTYH-associated polyposis, or MAP) is characterized by a greatly increased lifetime risk of colorectal cancer (CRC). Although typically …

2024年9月16日 · MUTYH- associated polyposis is an autosomal recessive polyposis syndrome. Affected patients have multiple colorectal adenomas and an increased risk for developing …

The MUTYH gene provides instructions for making an enzyme called MYH glycosylase, which is involved in the repair of DNA. This enzyme corrects particular errors that are made when DNA …

Mutations in this gene result in heritable predisposition to colorectal Cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been …

MUTHH息肉病综合征是一种罕见的常染色体隐性遗传疾病，可导致<1%的癌症。 临床表现类似其他形式的结直肠息肉或癌症。 诊断通过基因检测。 患者还需要定期结肠镜检查筛查其他癌 …

如今，由mutyh基因纯合变异引发的结肠癌已不再令人意外，而由杂合变异引起的严重病变则鲜有报道。 本文结果强调，当存在携带这种基因变异的患者时，需要进行更密切的随访，建议患 …