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Minute Virus of Mice (MVM) is an autonomous parvovirus of the Parvoviridae family that replicates in mouse cells and transformed human cells. MVM genomes localize to cellular sites of DNA damage with the help of their essential non-structural phosphoprotein NS1 to establish viral replication centers.

Minute virus of mice (MVM) is one of the most frequent viral pathogens in laboratory mice. Interestingly, this high prevalence occurs not only in conventionally housed mice but also in mice maintained behind strict barrier systems and monitored by …

During an epidemiological investigation of mice naturally infected with parvoviruses, our laboratory identified a strain of MVM that is distinct from the previously reported prototype (MVMp), immunosuppressive (MVMi) and Cutter (MVMc) strains of MVM.

The DNA damage response to infection with minute virus of mice (MVM) leads to activated p53; however, p21 levels are reduced via a proteasome-mediated mechanism. This loss was sustained, as virus replicated in infected cells held at the G 2 /M border.

2016年10月15日 · Minute virus of mice (MVM), a single-stranded deoxyribonucleic acid Parvovirus, was subjected to various inactivation procedures, including chemical disinfectants, heat, and ultraviolet radiation. MVM was found to be …

The parvovirus minute virus of mice (MVM) packages a single copy of its linear single-stranded DNA genome into preformed capsids, in a process that is probably driven by a virus-encoded helicase. Parvoviruses have a roughly cylindrically shaped pore that surrounds each of the 12 5 …

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Isolation and Characterization of Intermediates in the Replication of the Viral Deoxyribonucleic Acid. The time course of the appearance of intracellular viral DNA has been studied in mouse L cells infected with the single-stranded DNA virus MVM (minute virus of mice) by using a selective extraction procedure.

Characteristics of maternal vascular malperfusion (MVM) are frequently observed in placentas from pregnancies impacted by preeclampsia, intrauterine growth restriction, preterm labor, and intrauterine fetal demise. We sought to evaluate the ...