2024年12月25日 · MYO7A (Myosin VIIA) is a Protein Coding gene. Diseases associated with MYO7A include Usher Syndrome, Type I and Deafness, Autosomal Recessive 2. Among its …

The MYO7A gene provides instructions for making a protein called myosin VIIA, which is part of a group of proteins called unconventional myosins. Learn about this gene and related health …

The MYO7A gene encodes a protein classified as an unconventional myosin. Unconventional myosins are motor molecules with structurally conserved heads that move along actin filaments.

MYO7A is an unconventional myosin motor protein (3, 4), expressed both in retinal photoreceptors and the retinal pigmented epithelium (RPE) (5, 6). Studies of shaker1 mice …

Mutations in MYO7A (myosin VIIa) cause Usher syndrome type 1B, a disorder involving profound congenital deafness and progressive blindness. In the retina, most MYO7A is localized in the …

The second MyTH4-FERM myosin critical in setting hair bundle architecture is MYO7A, which localizes along the stereocilia shaft and at sites where extracellular stereociliary links insert …

2025年1月4日 · Title: Novel compound heterozygous synonymous and missense variants in the MYO7A gene identified by next-generation sequencing in a Chinese family with nonsyndromic …

MYO7A is the gene associated with the Usher syndromes. A genome-wide scan found linkage to locus DFNA11. Sequencing of the MYO7A gene in the linked region identified a new missense …

2024年3月5日 · New splice site mutations in MYO7A causing Usher syndrome type 1: a study on a Chinese consanguineous family. Novel compound heterozygous synonymous and missense …

Phagosome digestion and melanosome motility were studied in human primary RPE cells. RNAi knockdown studies showed that MYO7A functions to constrain rapid, long-range movements …