The study presented here reports on the use of lipopolysaccharide (LPS) challenge in cynomolgus macaques to induce predictable inflammatory cytokine responses. The results showed that IL …

2022年3月21日 · To address this gap, we used our established HCA model, in which pregnant Rhesus macaques receive intraamniotic (IA) saline or LPS. IA LPS induced a potent and rapid …

2016年11月25日 · Cultured cells from individual rhesus macaques were incubated with or without lipopolysaccharide (LPS), the powerful Gram-negative bacterial stimulant of inflammation. LPS …

2023年11月17日 · We recently reported that injection of lipopolysaccharide (LPS) in the amniotic space in pregnant Rhesus macaque at about 80% term gestation closely mimics human …

2022年4月5日 · We obtained CSF from 82 cynomolgus and rhesus macaques with the goal of obtaining reference ranges for core biomarkers of neurodegenerative disease for NHPs. LPs …

We performed tests in lipopolysaccharide (LPS)-induced acute neutrophilic inflammation in three species – human, rhesus macaque, rat – with increasing dose-dependent severity.

2016年9月6日 · Rhesus macaque fetuses were exposed to either intra-amniotic (IA) saline, or IA lipopolysaccharide (LPS) (1 mg) 16 or 48 h prior to delivery at 130 days (85 % of gestation) (n …

Background: Our previous study has established a macaque model with early-phase endotoxic shock. The present study further investigated myocardial and blood vessel injury in Macaques …

2019年8月29日 · The LPS challenge procedure in cynomolgus macaques presented here highlights that in cases where it is required, the use of a relevant immune response can be a …

2021年1月7日 · To define the triggers for PTL, we developed Rhesus macaque models of IUI driven by lipopolysaccharyde (LPS) or live E. coli. PTL did not occur in LPS challenged …