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Clinical manifestations of mannan-binding lectin deficiency
Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of …
甘露聚糖结合凝集素 - 百度百科
甘露聚糖结合凝集素(英语:Mannose-binding lectin,缩写MBL,也被称为甘露糖结合蛋白或甘露聚糖结合蛋白,英语:mannan-binding protein,缩写MBP)是一种在先天免疫系统中起作用 …
Mannan-binding lectin: clinical significance and applications
2002年9月19日 · Mannan-binding lectin (MBL) is a collectin (protein with both collagen-like and C-type lectin domains) synthesised in the liver and secreted into the bloodstream. Its plasma …
- 作者: David C Kilpatrick
- Publish Year: 2002
The Lectin Pathway of the Complement …
The molecule after which the lectin pathway derived its name is mannose-binding lectin (MBL), previously also called mannan-binding lectin, mannan-binding protein (MBP), and P28/P32 of the Ra-reactive factor (Ra-RF) [5,16,17]. In …
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Mannose-Binding Lectin in Human Health and Disease
2021年3月13日 · Degn SE, et al. Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway …
Mannan-Binding Lectin - an overview | ScienceDirect Topics
2010年3月1日 · Mannan-binding lectin (MBL) is an oligomeric lectin (based on a homotrimeric structural unit) which recognizes neutral sugars (mannose and N-acetylglucosamine) on …
Introduction to mannan-binding lectin - PubMed
Mannan-binding lectin (MBL) was first discovered as a plasma opsonin for baker's yeast and was independently characterized biochemically. It belongs to the small subfamily of collectins: C …
Mannan binding lectin and its interaction with immunoglobulins in ...
2006年8月15日 · Mannan binding lectin (MBL), the 'recognition' molecule of the lectin pathway of complement activation, is homologous in structure to C1q, and binds in a calcium-dependent …
The mannan-binding lectin pathway of complement activation
Mannan-binding lectin (MBL) is a plasma protein found in association with several serine proteases (MASPs) forming the MBL complex. MBL recognises carbohydrate structures …