2024年12月25日 · MAP2 (Microtubule Associated Protein 2) is a Protein Coding gene. Diseases associated with MAP2 include Central Neurocytoma and Olivopontocerebellar Atrophy. Among its related pathways are TGF-Beta Pathway and CNTF Signaling. Gene Ontology (GO) annotations related to this gene include structural molecule activity and calmodulin binding.

The single MAP2 gene produces four major transcripts producing four proteins, MAP2A, MAP2B, MAP2C and MAP2D. MAP2A and MAP2B are very high molecular weight proteins, with …

Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic marker. It influences microtubule dynamics and microtubule/actin interactions to control neurite outgrowth and synaptic functions, similarly to the closely related MAP Tau.

2025年3月8日 · Gene target information for MAP2 - microtubule associated protein 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Microtubule-associated proteins (MAPs) are a family of proteins that influence this property. We showed previously that MAP2, a neuron-specific protein that stabilizes microtubules in the dendrites of postmitotic neurons, is induced in primary cutaneous melanoma but is absent in metastatic melanomas.

2004年6月1日 · Microtubule-associated proteins (MAPs) of the MAP2/Tau family include the vertebrate proteins MAP2, MAP4, and Tau and homologs in other animals. They are best known for their microtubule-stabilizing activity roles regulating microtubule networks ...

2018年3月25日 · The 1.5 Mb microdeletion on 2q34 in our patient is the shortest microdeletion spanning MAP2, a top candidate gene responsible for autism and developmental delay, reported so far.

General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene …

2024年12月25日 · METAP2 (Methionyl Aminopeptidase 2) is a Protein Coding gene. Diseases associated with METAP2 include Microsporidiosis and Liver Rhabdomyosarcoma. Among its related pathways are Visual phototransduction and Arg/N-end rule pathway (eukaryotic). Gene Ontology (GO) annotations related to this gene include RNA binding and aminopeptidase activity.

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis.