2024年12月25日 · MAP6 (Microtubule Associated Protein 6) is a Protein Coding gene. Diseases associated with MAP6 include Cardia Cancer and Osteogenesis Imperfecta, Type X. Gene Ontology (GO) annotations related to this gene include microtubule binding and calmodulin binding. An important paralog of this gene is MAP6D1.

Microtubule-associated protein 6 (MAP6) or stable tubule-only polypeptide (STOP or STOP protein) is a protein that in humans is encoded by the MAP6 gene. [5][6] This gene encodes a microtubule-associated protein (MAP). The encoded protein is a calmodulin binding, and calmodulin-regulated protein that is involved in microtubule stabilization.

2024年12月9日 · This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene.

Here, we show that MAP6, previously known to confer cold stability to microtubules, promotes growth. More unexpectedly, MAP6 localizes in the lumen of microtubules, induces the microtubules to coil into a left-handed helix, and forms apertures in the lattice, likely to relieve mechanical stress.

2024年12月9日 · MAP6 is present at the Golgi complex and in secretory vesicles in unpolarized cells and re-distributed to newly forming axons, where it binds and stabilizes axonal microtubules. A palmitoylation cycle controls MAP6 membrane-microtubule shuttling and is required for its polarized distribution in axons.

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene.

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene target information for MAP6 - microtubule associated protein 6 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Discover the gene map of chromosome 6, a comprehensive resource showcasing the location and function of genes on this crucial chromosome. Explore genetic research, disease associations, and the impact of genetic variation on human health.

MAP6 cDNA / gene is a gene with protein product which located on 11q13.5. The MAP6 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish. 216 organisms have orthologs with human gene MAP6.