2024年12月25日 · MAPK8 (Mitogen-Activated Protein Kinase 8) is a Protein Coding gene. Diseases associated with MAPK8 include Hepatitis C and Hepatitis. Among its related …

Mitogen-activated protein kinase 8 (also known as JNK1) is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene. [5][6] The protein encoded by this gene is a member of the …

Enables JUN kinase activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including JNK cascade; generation of neurons; and positive regulation of …

丝裂原活化蛋白激酶 （mitogen-activated protein kinase，MAPK）是一组能被不同的细胞外刺激，如 细胞因子 、 神经递质 、激素、细胞应激及细胞黏附等激活的丝氨酸-苏氨酸 蛋白激酶。 …

MAPK通路有4种主要的分支路线： ERK 、 JNK 、 p38 /MAPK和ERK5。 其中，JNK和p38功能相似，跟炎症、凋亡、生长都有关；ERK主要管细胞生长、分化，其上游信号是著名的 Ras/Raf …

MAPK8 expression is associated with a quantitative trait locus in patients with sickle cell disease and pulmonary hypertension. Our results imply that mesenchymal JNK has a pivotal role in the …

丝裂原活化蛋白激酶 (mitogen-activated protein kinase，MAPK)级联系统是真核生物细胞中高度保守的信号系统之一，参与诸多生物学过程的调控。 在细胞因子、神经递质及激素等不同信号 …

2025年2月8日 · Title: MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis. JNK mediates cell …

MAP 激酶作为多种生化信号的整合点，参与多种细胞过程，如增殖、分化、转录调控和发育。 这种激酶被各种细胞刺激激活，并靶向特定的转录因子，因此介导响应细胞刺激的即刻早期基因 …

Mitogen-activated protein kinase 8 (also known as JNK1) is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene (10q11.22). MAPK8 is involved in multiple intracellular …