Looking for online definition of margination in the Medical Dictionary? margination explanation free. What is margination? Meaning of margination medical term. What does margination mean?

The meaning of MARGINATION is the act or process of forming a margin; specifically : the adhesion of white blood cells to the walls of damaged blood vessels. How to use margination in a sentence.

Margination is a critical first step in the process of pathogen recognition and phagocytosis by leukocytes. By adhering to the endothelial lining of blood vessels, leukocytes such as neutrophils and monocytes are able to leave the bloodstream and …

This margination process is generally attributed to red blood cells (which normally pile up behind the larger leukocytes in capillaries) that overtake the leukocytes and tend to push them toward the venular wall.

Neutrophils extravasate from blood vessels to the site of tissue injury or infection during the innate immune response.. In immunology, leukocyte extravasation (also commonly known as leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes (white blood cells) out of the circulatory system (extravasation) and …

2014年5月7日 · To facilitate the adhesion, white blood cells migrate toward the vessel walls in blood flow through a process called margination. The margination of white cells depends on a number of conditions including local hematocrit, flow rate, red blood cell aggregation, and the deformability of both red and white cells.

Leukocyte margination is defined by the flow of leukocytes in a position close to the endothelial surface rather than in the central blood stream, depends on the interaction between individual red and white blood cells, and is enhanced in small postcapillary venules, which represent the main location for leukocyte recruitment . Margination is ...

2000年5月1日 · I.A.1. Traffic and Margination. Neutrophils are partitioned in the blood between a circulating pool, present in large blood vessels and in the axial stream of small vessels, and a marginating...

“Margination” refers to the movement of particles in flow toward the walls of a channel. The term was first coined in physiology for describing the behavior of white blood cells (WBCs) and platelets in blood flow.

Margination refers to the migration of particles toward blood vessel walls during blood flow. Understanding the mechanisms that lead to margination will aid in tailoring the attributes of drug-carrying particles for effective drug delivery.