2022年5月24日 · Here, we discuss the origins of mast cells and their diverse and plastic phenotypes that are influenced by tissue residence. We explore how divergent phenotypes …

Mast cells (MCs) are the immune cells distributed throughout nearly all tissues, mainly in the skin, near blood vessels and lymph vessels, nerves, lungs, and the intestines. Although MCs are …

Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype, and …

This review summarizes the current understanding of the role of mast cells in many pathophysiological conditions. Keywords: mast cell, immune system, inflammatory mediators, …

2024年11月25日 · This review provides an overview of the latest developments in the MC field, with a focus on our evolving understanding of MC progenitors, MC heterogeneity across …

2021年10月5日 · In this Review, we discuss the existing and emerging therapies that target mast cells, and we consider how these treatments can help us to understand mast cell functions in …

In this review, we focus particularly on new insights into mast cell biology, with a focus on mast cell development, recruitment, heterogeneity, and reactivity. We also highlight the …

In this Review the authors describe the key attributes of mast cells that make them well suited to initiate and coordinate innate and adaptive immune responses to pathogens, by acting as...

We also review the epidemiology, pathogenesis, and diagnosis of MCAS in a broader context and to examine the signs and symptoms that occur due to its clinical relationship with other systems.

2025年3月21日 · This article provides a comprehensive overview of therapeutic approaches targeting mast cells, making it highly relevant to the treatment theme. It discusses the role of …