Troponin indicates pathophysiologic muscle damage when the measured value is greater than the 99th percentile of the normal range, about three standard deviations above the mean. [20] .

2022年3月17日 · Troponin levels usually increase sharply within three to 12 hours after a heart attack and peak about 24 hours after the heart attack. They will also remain high for several days. Why would I need this test? The most common use of …

2011年11月22日 · Assays for cTn, namely cTnI and cardiac troponin T (cTnT), are the preferred diagnostic tests for ACS, in particular non–ST-segment–elevation myocardial infarction, because of the tissue-specific expression of cTnI and cTnT in the myocardium. The results of cTn testing often guide the decision for coronary intervention.

2021年5月16日 · We characterized all troponin elevations ≥0.04 ng/mL from patients hospitalized with an ICD diagnosis of AMI across a diverse health system from 2012-2019. We grouped events into exponential categories of peak troponin and compared troponin levels to 1-year outcomes. We performed chart reviews for patients with troponin >400 ng/mL.

Troponin T (cTnT) and troponin I (cTnI) increase 2-3 hours after the onset of acute myocardial infarction. The maximum troponin value is observed in 12–48 hours. Troponin may be elevated for up to 2 weeks after a heart attack. The larger the infarction, the higher the troponin level and the longer the duration of elevated troponin levels.

2022年12月16日 · Elevated levels of troponin are usually a sign of heart damage. The heart damage could be caused by a heart attack or other stresses on the heart, such as very high blood pressure, congestive heart failure, inflammation of the heart (myocarditis) after a virus such as COVID-19, or another infection.

Our study demonstrates that maximum troponin level is a more sensitive and specific predictor of mortality than initial or change in troponin. Similarly, maximum troponin is the most predictive of AMI vs other causes of troponin elevation, likely because of the correlation between rising troponin levels and cardiomyocyte damage.

2014年11月20日 · What level of troponin indicates heart attack? The level of troponin that indicates a heart attack is the level above the reference range. For example if the normal reference range is listed as 0.00 – 0.40. Then 0.41 is technically positive although very weakly so, and 10 is very positive.

2023年10月1日 · Known as high-sensitivity troponin tests, they can detect heart attacks earlier and more accurately. A normal range differs for each type and brand of test. But in general, the normal range for women is zero to 10 nanograms per liter (ng/L); for men, it's zero to 14.

2021年6月25日 · Although the 99th percentile is the recommended diagnostic threshold for myocardial infarction, some guidelines also advocate the use of higher troponin thresholds to rule in myocardial infarction at presentation.