2024年12月25日 · MBL2 (Mannose Binding Lectin 2) is a Protein Coding gene. Diseases associated with MBL2 include Mannose-Binding Lectin Deficiency and Megalencephaly …

该蛋白质识别并结合许多微生物的甘露糖和 N-乙酰葡糖胺，包括细菌、酵母和病毒，包括流感病毒、HIV 和 SARS-CoV。 这种结合激活经典补体途径。 该基因的缺陷与自身免疫性疾病和传染 …

Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity [5][6] as an opsonin and via the lectin …

2025年2月8日 · MBP is a widely used alternative name for mannose binding lectin 2 (MBL2), which can be confused with the official symbol for MBP (myelin basic protein, GeneID 4155). …

MBL2 genotypes are independent determinants of HIV disease progression and heterozygosity for MBL2 coding mutations confer disease-retarding effects. data suggest that MBL2 variants …

Mannose-binding lectin 2 (MBL2), a member of the multimeric lectin family, is crucial in immune regulation and tumor development. MBL2 gene polymorphisms are associated with the risk …

2006年1月5日 · Mannose-binding lectin (MBL) is a collagen-like serum protein that mediates activation of the complement system and is of importance for host defence. Common variant …

2004年8月12日 · Human mannose-binding protein (MBL) is a component of innate immunity. To capture the common genetic variants of MBL2, we resequenced a 10.0 kb region that includes …

The MBL2 gene provides instructions for making a protein that assembles into a protein complex called mannose-binding lectin. Functional mannose-binding lectins are made up of two to six …

The MBL2 gene encodes a mannose-binding lectin (MBL), or protein (MBP), that is secreted by the liver as part of the acute-phase response and is involved in innate immune defense. The …