A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in ...
IL-25 and IL-33 are the predominant ILC2-inducing cytokines in this model. The presence of ILC2s in skin, and their production of type 2 cytokines in response to IL-33, identifies a role for …
Intelectin contributes to allergen-induced IL-25, IL-33, and
2017年2月22日 · The epithelial- and epidermal-derived cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) are upregulated during innate immune responses to allergen in asthma …
基于药物MOA诱导的过敏小鼠模型选择之特应性皮炎 - 知乎
MC903即 卡泊三醇，是一种维生素D3的低钙类似物，广泛用于治疗银屑病。 研究发现，局部使用MC903可激发小鼠上皮角质细胞高表达TSLP，促进CD4+T细胞向Th2细胞分化及激活并释放 …
Frontiers | Prolyl hydroxylase inhibition protects against murine MC903 …
2024年2月29日 · In this study, we investigated the protective effect of DMOG on MC903 (calcipotriol)-induced type 2 skin inflammation. Morphological and immunological changes …
A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in ...
Roles of IL-25, IL-33, and TSLP in skin swelling and inflammation and ILC2 infiltration in BALB/c mice strains. MC903 or vehicle was applied topically for 4 d to the ear of wild-type or knockout …
【合集】皮肤系统相关自免疾病动物模型|BioMice百奥动物
2024年10月14日 · 卡泊三醇（MC903），是一种维生素D3类似物，广泛用于治疗银屑病。 过去研究发现，局部使用MC903可激发小鼠上皮角质细胞高表达TSLP，促进CD4+T细胞向Th2细胞 …
Ultraviolet-treated riboflavin alleviates atopic dermatitis by ...
2025年3月19日 · This study investigates the potential of ultraviolet (UV)-treated riboflavin in AD treatment. Using a MC903-induced mouse model, we demonstrate that topical UV-treated …
2型固有淋巴样细胞在MC903诱导的小鼠特应性皮炎样反应中的作 …
为探讨ILC2在AD中的作用，我们使用卡泊三醇（MC903）诱导的AD样小鼠模型，采用流式细胞仪检测皮损中ILC2的比例，并通过抗体拮抗ILC2初步阐明ILC2在MC903诱导的AD样小鼠2型炎 …
A Mouse Model for Atopic Dermatitis Using Topical Application …
2017年1月7日 · Topical application of vitamin D3 or of its low-calcemic analog MC903 induces changes in skin morphology and inflammation resembling immune perturbations observed in …
TSLP Elicits IL-33–Independent Innate Lymphoid Cell ... - Science
2013年1月30日 · AD in humans is linked to cytokines interleukin-33 (IL-33), IL-25, and thymic stromal lymphopoietin (TSLP) in the skin. To this end, the authors investigated in mice …
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