A significant reduction of vessel length is observed at days 5 and 7 after MCAO. (C) Cleaved caspase-3 (CC3) immunohistochemistry and nuclear morphology reveal apoptosis of CD31+ endothelial...

2019年1月24日 · Low and high scale mapping of the glial activation on brain sections of mice subjected to 30 minutes middle cerebral artery occlusion (MCAO) was correlated with that of the neuronal cell death,...

2020年1月6日 · To examine whether OPCs had beneficial effect on endothelial cells after MCAO, we performed β-catenin/CD31 double staining. β-catenin was mainly expressed on the cerebral vasculature (Fig. 4a).

2016年2月13日 · MBP, Iba1, and CD31 immunostaining were performed to determine myelin lesion, microglia activation, and microvessel density. Clodronate liposomes depleted 80 % of the macrophages in the mouse spleen and reduced macrophage infiltration in the mouse brain.

2021年8月1日 · The mRNA and protein expression of CD31 were also assessed in the striatum and cortical region to estimate angiogenesis post MCAO. Our findings demonstrate that CM treatment could significantly ameliorate neurological deficits and infarct volume in MCAO rats.

2021年3月2日 · In a mouse model of middle cerebral artery occlusion (MCAO), we applied LIPUS (32 cycles, 193 mW/cm 2) to the whole brain 3 times in the first week (days 1, 3, and 5) after MCAO. We evaluated...

2024年10月26日 · We found that the cGAS-STING pathway was activated and expressed in neurons after MCAO. Dual-tDCS improved motor function and infarct volume, inhibited neuronal apoptosis, promoted the expression of neurotrophins (BDNF and NGF), CD31, and VEGF, and suppressed inflammation reaction after MCAO via the cGAS-STING pathway.

2017年10月20日 · 探讨电针（EA）在甘树（BL 18）和神舒（BL 23）对脑梗死灶周围血管内皮生长因子（VEGF）和血小板内皮细胞粘附分子-1（PECAM-1）/ CD31的影响在大脑中动脉阻塞（MCAO）大鼠中的作用及其可能的机制，从而为针灸治疗脑缺血性中风提供了新的策略。

Additionally, CD31 + /NG2 + cells in peri-infarct cortex and striatum were respectively increased by TMP (10, 20, 40 mg/kg) and TMP (20, 40 mg/kg) compared with the model group (p < 0.01), which...

目的研究康复训练对脑梗死大鼠梗死边缘区微血管生成及其超微结构以及血小板内皮细胞黏附分子-1（CD31）表达的影响。 方法采用线栓法制作大鼠左侧大脑中动脉闭塞（MCAO）模型。