The Anti-Melanoma (MCSP) antibody recognizes the melanoma-associated chondroitin sulfate proteoglycan (MCSP) antigen, also known as high molecular weight melanoma-associated …

Assessment of microsatellite instability and tumor mutational burden status. This test uses targeted next-generation sequencing to estimate tumor mutational burden and detect …

2010年11月23日 · Anti-MCSP:TRAIL was designed to 1. selectively accrete at the cell surface of MCSP-positive melanoma cells and inhibit MCSP tumorigenic signaling and 2. activate …

2010年11月23日 · Treatment of a panel of MCSP-positive melanoma cell lines with anti-MCSP:TRAIL induced TRAIL-mediated apoptotic cell death within 16 h. Of note, treatment …

MCSP 是黑色素瘤免疫治疗的成熟靶点，最近已被证明可以为黑色素瘤细胞提供重要的致瘤信号。 TRAIL 是一种非常有前途的杀肿瘤细胞因子，对正常细胞没有毒性或毒性很小。 Anti …

2020年8月19日 · The dual‐utilization OncoBean (DUO) device is conjugated with melanoma specific antibodies, MCAM and MCSP, enabling simultaneous CTC and exosome isolations. …

We first screened JWCI's panel of 35 melanoma cell lines to determine the level of MCSP surface expression. MCSP-negative and MCSP-positive cell lines were used to determine the antigen …

The dual-utilization OncoBean (DUO) device is conjugated with melanoma specific antibodies, MCAM and MCSP, enabling simultaneous CTC and exosome isolations.

2009年5月15日 · Melanoma-associated chondroitin sulfate proteoglycan (MCSP) (also known as high molecular weight-melanoma-associated antigen) represents an interesting target antigen …

2010年11月23日 · MCSP is a well-established target for melanoma immunotherapy and has recently been shown to provide important tumorigenic signals to melanoma cells. TRAIL is a …