2023年11月3日 · Corneal melt, or keratolysis, is a severe, albeit rare, eye condition characterized by the progressive dissolution of the corneal stroma, leading to corneal thinning and potentially, perforation. The cornea plays a crucial role in focusing light onto the retina, and any damage to it can significantly impair vision.

2012年10月1日 · A chemical injury of the eye presents a genuine, acute emergency and requires immediate evaluation and management. 1 Although the most devastating sequelae of chemical injuries—corneal melt, limbal stem cell deficiency, and glaucoma—tend to occur over the long term, effective diagnosis and treatment in the minutes and days following the ...

2012年7月6日 · Corneal ulceration remains a serious clinical condition. When this occurs with progressive corneal stromal dissolution, there are real risks of permanent sight loss. As ophthalmologists, we...

2016年10月1日 · Corneal perforations are ocular emergencies with myriad causes, such as trauma, infection, autoimmune diseases, and loss of corneal innervation. Knowledge of the cause of the perforation is essential for its proper management.

2002年11月15日 · A corneal melt, or peripheral ulcerative keratitis, is a serious condition that usually has an underlying systemic etiology. Collagen vascular disease is found in approximately 50% of all noninfectious peripheral ulcerative keratitis; rheumatoid arthritis is …

2019年10月3日 · Inflammatory corneal disorders can cause thinning with stromal melting. These conditions are often associated with pain, epithelial defects, corneal neovascularization, and other inflammatory changes. Progression is fast and emergent treatment is warranted upon diagnosis.

We present seven patients with immune mediated melts causing perforation or severe vision loss. Through this case series, we hope to highlight the importance of studying immune related corneal melts.

Corneal melting is a complication of dry eye syndrome and is a potentially blinding condition. Here we report a case of a 67-year-old patient who attended her general practitioner for a year complaining of persistent dry eyes.

Corneal melt, an ophthalmological condition in which corneal epithelium is lost accompanied by thinning of the corneal stroma, can lead to corneal perforation and cause loss of vision. Corneal melt is the most serious side effect of topical nonsteroidal anti-inflammatory drugs (NSAIDs), one of …