2023年5月22日 · Macrophages possess binary M1/M2 macrophage polarization settings, which perform a central role in an array of immune tasks via intrinsic signal cascades and, therefore, …

2021年3月24日 · Differential polarization of macrophage into M1 and M2 mediates atherosclerotic plaque clearance through efferocytosis. Higher expression of Mer proto-oncogene tyrosine …

Increased lactate levels promoted M2 macrophage polarization, thereby inhibiting CD8 + T cell activity. Mechanistically, SRSF10 interacted with the 3'-untranslated region of MYB, enhancing …

2025年3月7日 · In this review, we summarize the research history, origin heterogeneity, and polarization of tissue macrophages. We also discuss their biological functions and roles in …

Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. These markers are transmembrane glycoproteins, scavenger receptors, enzymes, …

macrophages can be induced to express inducible NOS (iNOS), generating NO and Th1 CD4 + T cells mediated immune response. In comparison, Balb/c albino mice added ornithine-like …

2024年10月4日 · Here, our single-cell RNA sequencing data identify a subpopulation of macrophages expressing high levels of the phagocytic receptor MER proto-oncogene tyrosine …

2023年5月22日 · Macrophages exist in various tissues, several body cavities, and around mucosal surfaces and are a vital part of the innate immune system for host defense against …

Here, we used combinations of “incoherent” stimuli – those that individually promote distinct macrophage phenotypes – to elucidate how the immunosuppressive, IL-10-driven …

We now show that activation of MerTK in human macrophages led to ERK-mediated expression of the gene encoding sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2), …