Metabolic cardiomyopathies can be caused by disturbances in metabolism, for example diabetes mellitus, hypertrophy and heart failure or alcoholic cardiomyopathy. Deficiency in enzymes of …

2020年9月9日 · Metabolic cardiomyopathies represent a large heterogeneous group of diseases caused by inborn errors of metabolism (IEM). So far, more than 1000 distinct disorders of …

Metabolic diseases affect the ability of the myocardium to function properly, and if left untreated, may lead to cardiomyopathy (CM), a potentially fatal myocardial disease. Pathologic …

2023年5月26日 · Metabolic changes in both cardiomyocytes and non-cardiomyocytes contribute to pathological remodelling of the heart. The new paradigm for studying metabolic remodelling …

2017年3月15日 · Metabolic cardiomyopathy is a chronic metabolic disease characterized by structural and functional alterations and interstitial fibrosis without coronary artery disease or …

2022年5月9日 · Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease with heterogeneous clinical presentations, governed by multiple molecular …

2021年10月3日 · Chronic low-grade inflammation progressively alters metabolic processes in the heart, leading to a metabolic cardiomyopathy (MC) phenotype and eventually to heart failure …

2017年3月3日 · Metabolic cardiomyopathy is a chronic metabolic disease characterized by structural and functional alterations and interstitial fibrosis without coronary artery disease or …

Cardiovascular disease has long been recognized as a signif-icant contributor to morbidity and mortality in children and adults with inherited metabolic disorders.

2018年6月15日 · Herein, we provide an overview of recent insights on metabolic changes in genetic hypertrophic cardiomyopathy and discuss several therapies, which may be explored to …