Five-prime cap - Wikipedia
In eukaryotes, the 5′ cap (cap-0), found on the 5′ end of an mRNA molecule, consists of a guanine nucleotide connected to mRNA via an unusual 5′ to 5′ triphosphate linkage. This guanosine is …
mRNA capping: biological functions and applications - PMC
The 5′ m7G cap is an evolutionarily conserved modification of eukaryotic mRNA. Decades of research have established that the m7G cap serves as a unique molecular module that …
美国APExBIO中文官网 - mCAP
真核生物和病毒的mRNA在5'起始端有一个单甲基化修饰的帽子结构，m7G（5'）ppp（5'）G或称为mCAP。 Cap类似物在多种细胞过程中起重要作用，比如蛋白合成的起始，避免核酸外切酶 …
Cap Analogs (帽类似物) - MCE-生物活性分子大师
7-Methyl-diguanosine triphosphate (m7Gp3G) 是一种帽类似物，可以整合到 mRNA 中，参与哺乳动物细胞的翻译和 mRNA 降解。 m7Gppm6AmpG 是一种三核苷酸 mRNA 5' 帽类似物，可用 …
Identification and characterization of the interaction between the ...
The eukaryotic translation initiation factor eIF4E directly binds the m 7 G cap and through this interaction plays key roles in many steps of RNA metabolism including nuclear RNA export …
Applications of Phosphate Modification and Labeling to Study …
2017年1月23日 · In this paper, we review approaches employed to develop cap-based molecular tools that could benefit biological studies, with the focus on phosphate-labeled and phosphate …
Control of mammalian translation by mRNA structure near caps
The 5′ methyl G cap is initially recognized by initiation factor eIF4E. Under favorable translation conditions, eIF4G serves as a scaffold bridging the ribosome to the mRNA cap by binding …
mCAP - APExBIO
mRNA of eucaryon and virus has a monomethylated cap structure, m7G(5')ppp(5')G or called mCAP, at the 5’-initiating terminal. The cap analog plays an important role in cellular …
5' capping - BiologyisLove
2024年6月25日 · 5′ capping is one of the methods of processing of eukaryotic pre-mRNA. Eukaryotic mRNA has a unique enzymatically appended cap structure consisting of 7- …
Anatomy of an mRNA | TriLink BioTechnologies
Eukaryotic mRNA has a 7-methyl-G cap (mCAP) at the 5' end. The cap protects the mRNA from nucleolytic degradation and recruits the ribosomal initiation complex to the start of the mRNA. …