
List of Mikoyan and MiG aircraft - Wikipedia
This is a list of aircraft produced by Russian Aircraft Corporation MiG, formerly Mikoyan, a Russian aircraft manufacturer.
Mikoyan-Gurevich PBSh-1 - Wikipedia
The Mikoyan-Gurevich PBSh-1 (Russian: Микоя́н и Гуре́вич ПБШ-1) was a proposed attack aircraft designed in the Soviet Union.
有丝分裂诱导基因6(MIG-6)可诱导人成纤维细胞发生提前衰老
有丝分裂诱导基因6 (mitogen-inducible gene-6,MIG-6)是一个抑癌基因, 是ErbB RTK 通路的负调控因子,抑制肿瘤细胞增殖.本文以人胚肺二倍体成纤维细胞为对象,研究MIG-6蛋白在细胞衰老中的作用.
Mig-6 Plays a Critical Role in the Regulation of Cholesterol ...
Mitogen Inducible Gene 6 (Mig-6) is an immediate early response gene that can be induced by various mitogens, stresses, and hormones. To identify the metabolic role of Mig-6 in the liver, we conditionally ablated Mig-6 in the liver using the Albumin-Cre mouse model (Albcre/+Mig-6f/f; Mig-6d/d). Mig-6d/d mice exhibit hepatomegaly and fatty liver.
Loss of MIG-6 results in endometrial progesterone resistance
2022年3月1日 · We report that MIG-6 is downregulated in the endometrium of infertile women with endometriosis and in a non-human primate model of endometriosis. We find ERBB2 overexpression in the endometrium...
抑癌基因MIG-6与肿瘤 - ccj.pku.edu.cn
2014年11月2日 · 有丝分裂诱导基因6(mig-6)基因位于含有肿瘤抑制基因的染色体区域(1p36),其编码蛋白质可作为骨架衔接蛋白发挥调节胞内信号转导的作用.在细胞内,mig-6基因在生长因子、激素以及各种压力刺激作用下,能增加其蛋白质的表达量,进而通过其不同的功能片段(crib区域 ...
Mig-6 is required for appropriate lung development and to …
2009年10月1日 · Here, we have identified the adaptor protein encoded by mitogen-inducible gene 6 [Mig-6; Errfi1 (ErbB receptor feedback inhibitor 1); RALT (receptor-associated late transducer); gene 33], a potential regulator of intracellular signaling, as a crucial regulator of vascularization and lung development.
Mig-6 suppresses endometrial cancer associated with Pten …
2014年12月12日 · Mig-6 is a mediator of progesterone signaling, and its activity can suppress unopposed-estrogen signaling. Therefore, our studies provide a potential new drug target for the intervention of metastatic human endometrial cancer.
MIG-6 is essential for promoting glucose metabolic ... - PubMed
2021年3月21日 · Mitogen-inducible gene-6 (MIG-6) has long been thought of as a feedback inhibitor that targets activated EGFR and suppresses the growth of tumors driven by constitutive activated mutant EGFR. Here, our bioinformatics and histological analyses uncover that MIG-6 is upregulated in TNBC and that MIG-6 upregulation is positively correlated with ...
Mig-6, signal transduction, stress response and cancer
2007年3月1日 · The mitogen-inducible gene-6 (Mig-6) is an immediate early response gene encoding a nonkinase scaffolding adaptor protein. Mig-6 gene expression can be rapidly and robustly induced under both normal and pathological scenarios by factors including hormones, growth factors, and stresses.
- 某些结果已被删除