2024年12月25日 · MIR107 (MicroRNA 107) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR107 include Alzheimer's Disease and Leukemia, Chronic Lymphocytic. Request up-to-date GeneHancer data Download GeneHancer data sheet. ... Genes around MIR107 on UCSC Golden Path with GeneCards custom tracks …

2025年2月8日 · miR-107 directly targeted MCL1 and activated ATR/Chk1 pathway to inhibit proliferation, migration and invasiveness of cervical cancer cells. CHGA 3'-UTR C+87T disrupts an miR-107 motif; it is the first data to prove that expression level of miR-107 may be a novel and valuable prognostic factor in glioma.

microRNA-107（miR-107）是具有多种疾病中起调节作用的miRNAs，在肿瘤细胞的生长、分化、增殖、发育、凋亡和代谢等多种过程中发挥重要作用，与多种肿瘤有关。

Results: MiR-107 is downregulated in colorectal cancer tissues and several human colorectal cancer cell lines. Low miR-107 expression often indicates a poor survival rate for colorectal cancer patients. MiR-107 suppresses the proliferation, migration and invasion of SW620 cells by negatively regulating transferrin receptor 1 (TFR1).

2020年9月3日 · In the present study, we found microRNA-107 (miR-107) enhanced radiosensitivity by regulating granulin (GRN) in prostate cancer (PC-3) cells. MiR-107 was downregulated and GRN was upregulated...

miR-107 regulates growth and metastasis of gastric cancer cells via activation of the PI3K-AKT signaling pathway by down-regulating FAT4. PURPOSE To investigate the effect of miR-107 on the growth and metastasis of gastric cancer (GC) and elucidate the probable mechanisms.

细胞TU212及TU686中过表达或敲减miR-107,检测喉癌细胞增殖、克隆形成及侵袭能力的变化。 结果:miR- 107在喉癌组织中的表达显著低于癌旁正常组织,而CACNA2D1的表达则正好相反,差异有统计学意义(P<

摘要: 目的 检测microRNA-107（miR-107）在卵巢癌中的表达水平，探讨其对卵巢癌细胞系侵袭转移的调控作用及分子机制。 方法 qRT-PCR法比较卵巢癌组织、正常卵巢组织、卵巢癌细胞系和正常卵巢上皮细胞中miR-107表达差异，用生物信息学的方法特异预测出miR-107靶基因 ...

2024年8月1日 · We identified miR-107 as a potent regulator of both CGA and GATA2, effectively suppressing their activity. Administration of miR-107 has been shown to enhance the sensitivity of both MDR GC cells and xenografts to chemotherapeutic agents both in vitro and in vivo.

2021年4月26日 · Our findings demonstrated that miR-107 downregulation leads to hepatocellular carcinoma cell resistance in HDACi via a cofilin-1-dependent molecular mechanism and ROS accumulation. Keywords: chemosensitivity; drug resistance; hepatocellular carcinoma; miR-107. Hepatocellular carcinoma is a common type of liver cancer.