2021年11月23日 · The miR-200 family of microRNAs (miRNAs) includes miR-200a, miR-200b, miR-200c, miR-141 and miR-429, five evolutionarily conserved miRNAs that are encoded in …

In molecular biology, the miR-200 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by binding and cleaving mRNAs or inhibiting …

2024年12月25日 · MIR200A (MicroRNA 200a) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR200A include Meningioma and Ovarian Cancer. Among …

The miR-200 family consisting of 5 members (miR-200a, -200b, -200c, -141, -429) is an emerging miRNA family that has been shown to play crucial roles in cancer initiation and metastasis, …

The miR-200 family includes five evolutionarily conserved miRNAs named miR-200a, miR-200b, miR-200c, miR-141 and miR-429 that are encoded in two clusters of hairpin precursors, each …

2011年11月25日 · In conclusion, our study demonstrates that miR-200a regulates the Keap1/Nrf2 pathway in mammary epithelium, and we find that epigenetic therapy can restore miR-200a …

2025年2月8日 · Most pancreatic cancers display hypomethylation and overexpression of miR-200a and miR-200b, silencing of SIP1 by promoter methylation, and retention of E-cadherin …

2014年2月6日 · To further characterise the biological role of miR-200a expression in CRC, in vitro miR-200a inhibition and overexpression were performed and the effects on cellular growth, …

The miR-200 family (miR-200a, -200b, -200c, -141, -429) has been shown to have critical suppressive effects on cell transformation, tumor growth, and self-renewal in multiple cancer …

2016年12月1日 · Abstract In the last decade, microRNAs (miRs or miRNAs) became of great interest in cancer research due to their multifunctional and active regulation in a variety of vital …