Mitragynine pseudoindoxyl is a μ-opioid receptor agonist and δ-opioid receptor antagonist. It is a G protein biased agonist at the μ-opioid receptor, which may be responsible for its favorable side effect profile compared to conventional opioids. [3]

Mitragynine pseudoindoxyl is a mu agonist/delta antagonist opioid with a signaling bias for G-protein-mediated signaling pathways in vitro and which produced potent antinociception in vivo.

2024年8月7日 · Mitragynine Pseudoindoxyl is a rearrangement product of 7-hydroxymitragynine, a metabolite of mitragynine. This rearrangement results in a compound with enhanced analgesic effects. It is notably more potent as an opioid agonist than the parent mitragynine, making it of interest for pain management.

2024年11月6日 · Mitragynine Pseudoindoxyl is a rearranged chemical product of Mitragynine, where the indole ring undergoes oxidation, causing the formation of spiro- pseudoindoxyl core in the end product. This altered chemistry gives it a unique pharmacological profile.

2025年2月4日 · Pseudoindoxyl (also known as mitragynine pseudoindoxyl) is a highly specialized kratom derivative that differs from traditional kratom powders and extracts. Unlike naturally occurring alkaloids like mitragynine and 7-hydroxy, pseudoindoxyl is not found in significant amounts in raw kratom leaves.

The present study demonstrates that mitragynine pseudoindoxyl, a novel alkaloid structurally different from other opioid agonists, acts on opioid receptors, leading to a potent inhibition of electrically stimulated contraction in the ileum through the micro-receptors and in mouse vas deferens through delta-receptors.

Mitragynine pseudoindoxyl | C23H30N2O5 | CID 44301701 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Has anyone tried the psuedoindoxyl tablets that recently became available? I bought one, it's 15 mg like the 7oh ones but I haven't heard any reviews yet.

Discover the unique properties and potential benefits of Mitragynine Pseudoindoxyl, a powerful compound derived from Kratom.

2024年4月23日 · 7ohm is like jet fuel for me, extremely stimulating. Pseudo is slow, warm, fuzzy and about 2.5 hours in I get real sleepy. There’s a common misconception that pseudo is ‘more potent’ than 7OH. While pseudo is indeed a stronger painkiller, it …