Fixed gold-tone crystal set bezel. Blue peacock motif dial with gold-tone hands. Dial Type: Analog. Quartz movement. Scratch resistant mineral crystal. Pull / push crown. Solid case back. Round case shape, case size: 36 mm, case thickness: 10 mm. Band width: 14 mm. Water resistant at 50 meters / 165 feet. Functions: hour, minute, second.

MKC-3946 是一种 IRE1α 内切核糖核酸酶结构域抑制剂，可阻断 XBP1 mRNA 剪接并触发 MM 细胞的适度生长抑制。 MKC-3946 以剂量依赖性方式抑制 Tm 诱导的 XBP1s 表达，但不影响 IRE1α 的磷酸化。 MKC-3946 阻断 XBP1 剪接并增强 bortezomib 或 17-AAG 诱导的细胞毒性。 MKC-3946 (10 μM) 增强 bortezomib 或 17-AAG 诱导的 ER 应激介导的细胞凋亡，并增强 ER 应激源的细胞毒性，即使存在 BMSC 或外源性 IL-6 时也是如此 [3]。 MCE has not independently …

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IRE1α Inhibitor, MKC-3946, XBP1 expression blocker, MKC3946, MKC 3946. storage temp. A cell-permeable compound that binds to the endoribnuclease domain of IRE1α and inhibits its activity. Blocks XBP1 mRNA splicing in RPMI 8226 human multiple myeloma cells.

Original Michael Kors Watch Sofie For Women MK3946 Blue Green dial Rose Gold Metal Strap Color . Japanese Machine With packing MK Box + Bag. Get it inside Egypt within 24 hours, and inspect the product inside Cairo before paying Shipping to all of Egypt and the world

MKC3946是 IRE1α endoribonuclease domain 的可溶性抑制剂，在多种骨髓瘤细胞株中引起适度的生长抑制作用，而不对正常单核细胞具有毒性作用。 在骨髓瘤细胞系中，MKC-3946引起中等程度的细胞生长抑制，而正常单核细胞没有毒性作用。 它还显著地增强了bortezomib或17-AAG诱导的细胞毒性，即使在有骨髓基质细胞或内源性IL-6的情况下。 bortezomib和17-AAG能够诱导内质网应激反应，诱导XBP1的表达和细胞凋亡，而这些效应可被MKC-3946增强。 MKC-3946的 …

Michael Kors Women’s Quartz Gold Stainless Steel Blue Peacock Motif Dial 36mm Watch MK3946. Brand New. 100% Original. Comes with Michael Kors Packaging. 1 (One) year Official Royal Wrist Warranty. 7 Days Return & Exchange Policy: (click here for T&C) For Delivery and info: 03080122278. About this product. Product Identifiers

The model number is MK3946. This is a Michael Kors Sofia wristwatch for women, featuring a gold case with Roman numerals on the analog display. The watch has a quartz movement, water-resistant feature, and a solid caseback. It is adorned with crystal detailing and has …

The Michael Kors Sofie ladies watch (MK3946) combines sophisticated design with practical functionality. Featuring a 36mm round stainless steel case and a solid case back, it offers durability and timeless appeal.

Buy Michael Kors Multi-colored/Yellow gold toned steel Ø36 mm,model MK3946 with TheWatchAgency™. Material & Measurements Model:MK3946 Manufacturer.. 90 Day Return Policy