The mechanism by which endogenous salicylic acid (SA) regulates leaf senescence remains elusive. Here we provide direct evidence that an enhancement of endogenous SA level, via chemical-induced upregulation of ISOCHORISMATE SYNTHASE 1 (ICS1), could significantly accelerate the senescence process of …

Mitogen-activated protein kinases (MAPKs) form tightly controlled signaling cascades that play essential roles in plant growth, development, and defense response. However, the molecular mechanisms underlying MAPK cascades are still very elusive, largely because of our poor understanding of how they relay the signals.

2016年7月15日 · Mitogen-activated protein kinase (MAPK) cascades play a crucial role in plant growth and development, as well as their biotic and abiotic stress responses. As a nodal point of the MAPK cascade, the...

kinase kinase, MAPKK或MKK或MEK或MAP2K) 及MAPK 三种蛋白激酶逐级磷酸化传递信号 (Schaeffer和Weber 1999)。当细胞表面的模式识别 受体(pattern recognition receptor, PRRs)感受到胞 外刺激, 随即发生同源或异源二聚化, 进而磷酸化 细胞质中的受体类胞质激酶(receptor-like …

2022年1月5日 · Mitogen-activated protein kinase (MAPK) cascades are key signaling modules downstream of receptors/sensors that perceive either endogenously produced stimuli such as peptide ligands and damage-associated molecular patterns (DAMPs) or exogenously originated stimuli such as pathogen/microbe-associated molecular patterns (P/MAMPs), pathogen-derived...

2020年1月8日 · We reveal a MAPK cascade, MKK4/5-MPK1, which not only phosphorylates the key SA signaling component NPR1 specifically, but also regulates its oligomer-to-monomer conformational change somehow via mediation of TRX-h3/5.

2013年6月11日 · Transcriptional responses of a subset of canola MKK and MPK genes to stimuli including fungal pathogens, hormones and abiotic stress treatments were analyzed through real-time RT-PCR and we identified a few of BnaMKKs and BnaMPKs responding to salicylic acid (SA), oxalic acid (OA), Sclerotinia sclerotiorum or other stress conditions.

植物中的 ROS 稳态涉及丝裂原激活蛋白激酶 (MAPK) 途径，该途径由 MAPK 激酶激酶 MEKK1 和 MAPK MPK4 组成。 表型和分子分析表明，MAPK 激酶 MKK1 和 MKK2 是级联反应的一部分，调节 ROS 和水杨酸 (SA) 的积累。 基因表达分析显示，在 32 个据报道对多种 ROS 诱导条件高度响应的转录因子中，有 20 个受 MEKK1 调节，主要通过 MEKK1–MKK1/2–MPK4 途径。 然而，MEKK1 还在其他未知途径上发挥作用，并且部分 MEKK1 依赖性 MPK4 反应的调节独立于 …

2020年1月8日 · Taken together, our data demonstrate that the MKK4/5-MPK1/2 cascade plays a critical role in modulating SA signaling through a complex regulatory network in Arabidopsis. We reveal a MAPK cascade, MKK4/5-MPK1, which not only phosphorylates the key SA signaling component NPR1 specifically, but also regulates its oligomer-to-monomer conformational ...

2020年4月20日 · 丝裂原激活的蛋白激酶激酶（MAPKK或MKK）是MAPK级联反应的重要组成部分，在植物生长发育以及各种胁迫反应中起着重要作用。 目前，已经在多种植物中鉴定了MKK基因家族，但是在十字花科植物拟南芥中尚未进行系统的研究。 为了探索拟南芥中MKK基因家族的进化和功能，通过全基因组分析从拟南芥中鉴定出16个ApMKK基因，并将它们分布在拟南芥的10条染色体上。 根据系统发育分析和多序列比对，将这些推定基因分为五个已知的亚家族， …