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Since 2006, MLH, Inc.'s Arti Rolfingsmeier has been a "ghost-writer" and researcher for Kansas and Missouri attorneys. Arti Rolfingsmeier is a licensed Kansas attorney*, who, through MLH, Inc. (formerly My Learned Hand), contracts only to other attorneys to provide her research and writing skills rapidly and on point. * on inactive status.

Main Line Health is home to four of the region’s most respected acute care hospitals—Lankenau Medical Center, Bryn Mawr Hospital, Paoli Hospital and Riddle Hospital—as well as one of the nation’s premier facilities for rehabilitative medicine, Bryn Mawr Rehabilitation Hospital.

Mixed lineage kinases (MLKs) are mitogen activated protein kinase kinase kinases (MAPKKKs) with features of both serine-threonine and tyrosine kinases that regulate the c-Jun N-terminal kinase (JNK) mitogen activated protein kinase (MAPK) signaling cascade, and also regulate p38 and extracellular signal-regulated kinase (ERK).

2007年4月4日 · MLKs were identified initially as signalling molecules in the nervous system. They were also shown to play a role in the cell cycle. Further studies documented three groups of MLKs, and showed that they may be activated via the c-Jun NH 2 terminal kinase (JNK) pathway, and by Rho GTPases.

MLKs were identified initially as signalling molecules in the nervous system. They were also shown to play a role in the cell cycle. Further studies documented three groups of MLKs, and showed that they may be activated via the c-Jun NH (2) …

2022年4月24日 · 该研究揭示了 MLKs在细胞核内通过磷酸化FREE1蛋白，调控FREE1蛋白核定位和核积累，从而负调控植物ABA信号的全新功能。 华南师范大学 高彩吉教授为通讯作者，博士后 黎洪波、硕士研究生 魏娟和 廖阳斓为共同第一作者；香港中文大学庄小红教授和华南师范大学张钟徽教授参与了该项研究工作。 本研究主要得到了国家自然科学基金、广东省自然科学基金以及霍英东教育基金会青年教师基金等项目的支持。 全文链接： …

2019年6月28日 · 混合谱系激酶（MLKs）是丝裂原活化蛋白激酶激酶激酶（MAPKKK），具有调节c-Jun N末端激酶（JNK）丝裂原活化蛋白激酶（MAPK）信号级联的丝氨酸 - 苏氨酸和酪氨酸激酶的特征，以及还调节p38和细胞外信号调节激酶（ERK）。 MLK3（MAP3K11）是最广泛表达的MLK家族成员，并且在神经元（以及其他细胞类型）中表达。 在细胞水平，MLK3被应激激活，包括活性氧，神经酰胺和TNFα。 在分子水平上，它被Cdc42和Rac活化，其与MLK3相互作用， …

Mixed lineage kinases (MLKs) are mitogen activated protein kinase kinase kinases (MAPKKKs) with features of both serine-threonine and tyrosine kinases that regulate the c-Jun N-terminal kinase (JNK) mitogen activated protein kinase (MAPK) signaling cascade, and also regulate p38 and extracellular signal-regulated kinase (ERK).

1997年2月1日 · Regulation of the mitogen-activated protein kinase (MAPK) family members — which include the extracellular response kinases (ERKs), p38/HOG1, and the c-Jun amino-terminal kinases (JNKs) — plays a central role in mediating the effects of diverse stimuli encompassing cytokines, hormones, growth factors and …