Mixed lineage kinase domain like pseudokinase - Wikipedia
Mixed lineage kinase domain like pseudokinase (MLKL) is a protein that in humans is encoded by the MLKL gene. [5] This gene belongs to the protein kinase superfamily. The encoded protein …
MLKL Gene - GeneCards | MLKL Protein | MLKL Antibody
2024年12月25日 · MLKL (Mixed Lineage Kinase Domain Like Pseudokinase) is a Protein Coding gene. Diseases associated with MLKL include Maturity-Onset Diabetes Of The Young and …
MLKL-USP7-UBA52 signaling is indispensable for autophagy in …
We identified UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1) as the binding partner of MLKL under physiological conditions. Loss of Mlkl induced a decrease in ubiquitin …
PROTACs Targeting MLKL Protect Cells from Necroptosis
2023年8月3日 · Mixed Lineage Kinase domain-Like pseudokinase (MLKL) is implicated in a broad range of diseases due to its role as the ultimate effector of necroptosis and has therefore …
MLKL mixed lineage kinase domain like pseudokinase [ (human)]
2025年2月8日 · Mixed Lineage Kinase Domain-Like Pseudokinase (MLKL) Gene Expression in Human Atherosclerosis with and without Type 2 Diabetes Mellitus. Location, location, location: …
MLKL: Functions beyond serving as the Executioner of Necroptosis
2022年3月1日 · Pseudokinase mixed lineage kinase domain-like protein (MLKL) serves as a terminal-known obligate effector in the process of necroptosis. To date, the majority of …
MLKL, the Protein that Mediates Necroptosis, Also Regulates …
2017年7月18日 · Activation of the pseudokinase mixed lineage kinase domain-like (MLKL) upon its phosphorylation by the protein kinase RIPK3 triggers necroptosis, a form of programmed …
The Many Faces of MLKL, the Executor of Necroptosis - PMC
Mixed lineage kinase domain-like (MLKL) protein is the main player of this cell death pathway as it mediates the final step of plasma membrane permeabilization. Despite the significant progress …
比利时根特大学：MLKL可以通过坏死依赖和非依赖功能影响肿瘤的 …
MLKL是坏死的刽子手，一个RIPK3依赖的过程。 坏死可能作为一种肿瘤抑制机制，并作为凋亡抵抗的备用. 2021年5月20日讯/ 生物谷 BIOON/---比利时根特大学研究者在Cell Death & …
CNS前沿文献追踪 – 追踪程序性坏死过程中MLKL行为 - 搜狐
2020年6月29日 · MLKL的行为追踪的差不多了，着手看它和细胞死亡的关系，先看看细胞死亡过程：TSI刺激细胞后，细胞膜出现损伤（Annexin V着色），损伤积累到一定程度后膜破 …