In this paper, we reviewed the pathophysiology of the depressive disorder and its current animal models with the analysis of their transcriptomic profiles. We provide insights for selecting …

Dec 20, 2023 · For example, Beck’s (1983) model of depression was influenced by psychoanalytic ideas such as the loss of self-esteem (re: Beck’s negative view of self), object …

Longer-term models include chronic mild stress models, early-life stress models, and social conflict models, which may more accurately simulate processes that lead to depression. These …

A unified model of depression should fulfill a number of requisites. First and foremost, it should integrate find-ings from various levels of analysis (e.g., genetic, psycho-logical) into a coherent …

The developmental model identified early traumatic experiences and the formation of dysfunctional beliefs as predisposing events and congruent stressors in later life as …

Jan 1, 2010 · Currently used models of depression attempt to produce quantifiable correlates of human symptoms in experimental animals. The models differ in the degree to which they …

Aug 9, 2024 · In this review, we mainly summarize the most widely used behavioral animal models and neural circuits under different triggers of depression, aiming to provide a …

Jan 14, 2021 · Early-life stress (prenatal stress, maternal separation, post-weaning social isolation), chronic-mild stress or social defeat stress models are the most validated and widely …

‘Models of depression’ highlights some of the most well-known biological, psychological, and social models ranging from the monoamine hypothesis to Beck’s cognitive model, and then …

Part 2 further delves into behavioral genetics, animal models of depression, and the role of sleep and circadian rhythms in depression. Part 3 examines individual differences and psychological …