The aim of the GERD consensus process was to determine modern indications for oesophageal testing in GERD, and as an extension to that aim, to define criteria for a clinical diagnosis of GERD. The consensus process started in 2014, when the primary aims were formulated, followed by a literature search and grading of evidence.

2022年7月21日 · Reflux esophagitis (RE) / gastroesophageal reflux disease (GERD) is the reflux of gastric contents into the esophagus that results in symptoms or complications; reflux esophagitis / gastroesophageal reflux disease is objectively defined as mucosal injury seen at endoscopy or abnormal esophageal acid exposure on a reflux monitoring study

2024年5月1日 · Identify the etiology of gastroesophageal reflux disease by integrating the patient's history with risk factors. Determine the appropriate strategy to diagnose gastroesophageal reflux disease considering the duration and frequency of exacerbations. Select the optimal management approach for a patient with gastroesophageal reflux disease.

2025年2月1日 · Relevant clinical outcomes included incidence of GERD symptoms, esophagitis, BE, objective endoscopic findings of GERD including adverse events and morphology of the antireflux barrier, improvement in GERD symptoms or remission, change in GERD symptom-related scores (GERD health-related quality of life [HRQL] or similar scale), PPI ...

The present definition of gastroesophageal reflux disease is based on clinical criteria that are difficult to reproduce accurately. Pathologists are supposed to confirm the presence of morphological changes induced by gastroesophageal reflux.

2017年9月27日 · GERD is a common condition worldwide. Key mechanisms of disease include abnormal oesophagogastric junction structure and function, and impaired oesophageal clearance. A therapeutic trial of...

2021年12月7日 · To assess the esophagogastric junction (EGJ) on real-time MRI and compare imaging parameters to EGJ morphology on high-resolution manometry (HRM).

All participants were classified into types 1 to 6 based on the gastric morphology determined from the first UGI. Cascade stomach is recognized by characteristic findings on UGI. Gastric types 2 and 3 tend to appear as cascade stomachs and were significantly associated with GER (P < .05) compared with the other groups.

2025年1月7日 · GERD classification (NERD or RE, A-D) was based on endoscopic findings. Reflux was assessed through 24-hour pH-impedance monitoring, and high-resolution esophageal manometry (HREM) measured parameters including EGJ-CI. Results: HREM revealed EGJ morphologies (type I, II, III) in 80.6%, 13.9%, and 5.6% of subjects, respectively.

I believe that these data support the adoption of novel histologic definitions of GERD as follows: the presence of any squamo-oxyntic gap defines GERD; the length of the gap is a measure of severity of chronic GERD; and the presence of intestinal metaplasia in the gap defines Barrett esophagus and c …