2023年11月6日 · In this study, we identify a fate switch comprised of the MKK3–MPK7 kinase cascade and the ethylene response factor ERF4 that is responsible for the seed state transition from dormancy to germination.

Constitutively active StMPK7 (CA-StMPK7; StMPK7 D198G, E202A ) was found to promote immunity to Phytophthora pathogens and to trigger host cell death when overexpressed in Nicotiana benthamiana leaves. Cell death triggered by CA-StMPK7 is SGT1/RAR1-dependent.

2023年9月13日， 中国农业科学院深圳农业基因组研究所 向勇课题组在Molecular Plant在线发表了题为“The MKK3-MPK7 cascade phosphorylates ERF4 and promotes its rapid degradation for releasing seed dormancy in Arabidopsis ”的研究论文。文章揭示了种子释放休眠启动萌发的新机制。

2023年11月6日 · The activated MKK3-MPK7 module phosphorylates ERF4, leading to its rapid degradation and thereby releasing its inhibitory effect on the expression of these EXPAs. Collectively, our work identifies a signaling chain consisting of protein phosphorylation, degradation, and gene transcription , by which the germination promoters within the embryo ...

2023年11月6日 · It provides insight into the awakening of dormant seeds by exploring three major aspects: (i) the involvement of the MKK3–MPK7 cascade, a crucial signaling pathway, in controlling seed dormancy; (ii) the elucidation of ERF4 as a substrate that negatively influences dormancy release, embryo expansion, and how degradation of ERF4 promotes dormancy...

2023年9月22日 · 近日，基因组所向勇课题组在《分子植物学（Molecular Plant）》上在线发表题为“The MKK3-MPK7 cascade phosphorylates ERF4 and promotes its rapid degradation for releasing seed dormancy in Arabidopsis ”的研究论文，鉴定了一个调控种子从休眠状态到萌发状态转变的“命运开关”，揭示了 ...

2015年2月27日 · In planta, we show that ABA activation of MPK7 is blocked in mkk3-1 and map3k17mapk3k18 plants. Coherently, both mutants exhibit hypersensitivity to ABA and altered expression of a set of ABA-dependent genes.

2025年2月17日 · Here, we show that nitrate resupply to nitrogen-depleted Arabidopsis (Arabidopsis thaliana) plants triggers, within minutes, an MAPK cascade that requires NLP-dependent transcriptional induction of mitogen-activated protein kinase kinase kinase 13 (MAP3K13) and MAP3K14 and that the MAPK cascade is composed of MKK3 and likely C-clade MAPKs (MPK1/...

2016年9月12日 · In this study, we found that MPK3 and MPK6 are the substrates for phosphorylation by MKK7 in planta. Genetic analysis showed that MKK7-MPK6 cascade is specifically responsible for the regulation of shoot branching, hypocotyl gravitropism, filament elongation, and lateral root formation, while MKK7-MPK3 cascade is …

In this study, we identify a fate switch comprised of the MKK3–MPK7 kinase cascade and the ethylene response factor ERF4 that is responsible for the seed state transition from dormancy to germination.