MT-ND6 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 6 protein (ND6). [5] The ND6 protein is a subunit of NADH dehydrogenase (ubiquinone), …

2024年12月25日 · MT-ND6 (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 6) is a Protein Coding gene. Diseases associated with MT-ND6 include Leber …

2025年2月8日 · Clinical resource with information about MT-ND6, Leber optic atrophy, MELAS syndrome, and available tests. There are links to practice guidelines and authoritative …

启用 NADH 脱氢酶 (泛醌) 活性。 参与线粒体电子传递、NADH 到泛醌和线粒体呼吸链复合体 I 的组装。 预测位于线粒体内膜。 与 Leber 遗传性视神经病变有关；利氏病；下肢为主的脊髓性 …

Maternally inherited non-syndromic hearing loss is linked with a novel mitochondrial ND6 gene mutation. Reduced mitochondrial-encoded NADH dehydrogenase 6 gene expression drives …

Each of the MT-ND6 gene variants changes a single protein building block (amino acid) in the NADH dehydrogenase 6 protein. One common MT-ND6 gene variant is responsible for about …

2025年1月4日 · Title: Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation. …

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in …

promotes GC progression by regulating mitochondrial respiratory function through the FASTK/MT-ND6 axis. Key words: Gastric cancer; Lnc-BM; FASTK; Mitochondrion Funding: National …

2021年6月18日 · mt-nd6作为新靶点在代谢综合征诊断和治疗药物中的应用，其机理为：mt-nd6基因能够调控线粒体功能、维持线粒体稳态，在制备改善线粒体功能失常相关疾病的药物中具有 …