Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the …

2024年12月25日 · The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD; …

The first identified was the μ (or mu) heavy chain that is present in all jawed fish and is the heavy chain for what is thought to be the primordial immunoglobulin. The resulting antibody, IgM, is …

IgM 结合的感染细胞的 Fc 区可以激活 补体蛋白 （参与第一道防线的一组血清蛋白），其级联激活许多其他补体蛋白，最终通过增强 吞噬细胞 的吞噬作用或通过形成膜攻击来破坏感染细胞复 …

IgM is another major antibody produced in the primary immune response to antigens. Although the IgM monomers are composed of two heavy and two light chains like IgG molecules, the …

Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell …

免疫球蛋白 (Ig) 是 B 细胞的抗原识别分子。 Ig 分子由通过二硫键连接的 2 条相同的重链和 2 条相同的轻链 (参见 MIM 147200) 组成，因此每条重链都连接到一条轻链，并且 2 条重链连接在一 …

2025年3月8日 · The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD; MIM …

2010年8月12日 · The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD; …

An Immunoglobulin Mu Chain is a type of heavy chain in immunoglobulins, characterized by its molecular weight of 50 to 75 kDa and its role in defining the conformation of the antigen …