2024年9月20日 · Mucus is a clear, slippery, gel-like substance that’s part of your immune system. It lines your mucous membranes and helps trap and destroy or clear out germs and harmful particles. Mucus gets thick and sticky and might be white, yellow or green when you have an infection. It’s also called phlegm, snot or sputum.

2022年6月22日 · Stanford University scientists have implicated a logjam of three long, stringy substances behind deadly thick sputum in COVID-19 patients who need a machine to help them breathe. One of these substances may prove especially amenable to treatment with a drug invented long ago for another purpose. It may also play a role in long COVID.

2024年11月1日 · Sometimes mucus secretions in the lungs can persist after someone starts to get better from a chest cold, flu, pneumonia, or COVID. To cope with the problem, experts recommend doing exercises that clear the lungs or strengthen respiratory muscles.

2023年8月16日 · We applied this technology to develop a mucosal vaccine for severe acute respiratory syndrome coronavirus 2 and found that intranasal vaccination with spike protein–encoding mRNA polyplexes induced potent cellular and humoral adaptive immunity and protected susceptible mice from lethal viral challenge.

2021年11月1日 · Based on the background information, we hypothesize that the drugs targeting elevated mucins or else implementing better ways to remove excess mucus clogs in airways can improve pulmonary complications in COVID-19 patients.

2025年1月20日 · Viral variant and host vaccination status impact infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), yet how these factors shift cellular responses in the human nasal...

Mucosal vaccines are promising for preventing infections and reducing the transmission, morbidity and mortality of COVID-19. Mucosal vaccination may be used prophylactically in human populations at high risk for severe acute respiratory syndrome coronavirus 2.

2021年7月26日 · Mucosal vaccination utilizing nucleic acids poses a greater challenge, as successful candidates must penetrate the mucus layer, translocate into target cells and evade extracellular and ...

The presence of mucus is best identified with special histochemical stains such as Alcian blue and/or periodic acid–Schiff or with immunohistochemical staining. This in turn raises the question whether we have underestimated the role of mucus dysfunction in other viral pneumonias.