已知在早期发育阶段 GC 中表达的基因是 Wt1 和 Foxl2；对于mural GC，Cyp19a1；对于卵丘细胞，Slc38a3 和 Amh；对于类固醇生成的 GC，Cyp11a1 和 Lhcgr。 标记基因 Wt1、Slc38a3 …

颗粒细胞 (granulosa cell)是卵泡内的体细胞,在卵泡的生长发育过程中发挥着至关重要的作用.随着卵泡发育至窦卵泡期,颗粒细胞分化为在空间和功能上不同的2个种群,即围绕在卵母细胞周围的 …

2019年7月18日 · Pseudotime analysis using Monocle 3 alpha, that places the progenitor cell population in the middle of a longer trajectory segment, revealed that pGC (CL15) branched to …

2021年6月5日 · Two different types of GCs, mural GCs and cumulus cells (CCs), serve different functions during folliculogenesis. Mural GCs produce oestrogen during the follicular phase and …

2024年2月14日 · We investigated the interactions between mural granulosa cells (MGCs) and cumulus granulosa cells (CGCs) during ovulation after the LH surge. We performed clustering, …

2015年8月27日 · Granulosa cells (GC) differentiate into two functionally distinct groups during ovarian follicle growth: cumulus cells (CC) that are in physical contact with the oocyte, and …

2021年9月2日 · Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle …

Black dashed lines give the boundaries of several clusters of GC (common progenitor GC (pGC), mural GC, cumulus GC, atretic GC (atrGC), theca cells (TC), and atretic TC (atrTC)). b tSNE...

Follicles in (early) stages of atresia (Fig. 1b) may resemble growing follicles (Fig. 1a) in size, but the cellular organization of mural GC and TC layers differ. Follicles in (early) stages of...

Granulosa cells (GCs) are somatic cells surrounding oocytes that differentiate into cumulus cells (CCs) and mural granulosa cells (MGCs) during the antral follicular phase.