一项最新研究发现，二次叶片牵引是严重退行性二尖瓣反流的一个重要机制，导致了一种名为MVPt+的表型。该研究对94例患有严重二尖瓣反流的二尖瓣脱垂病人和21名健康对照进行了前瞻性评估。

ROC curve revealed that a 3D VCA ≥ .55 cm 2 is the optimal cutoff point to predict MVPt+ phenotype. Conclusions: Secondary leaflet tethering is a significant mechanism behind severe degenerative MR, resulting in an MVPt+ phenotype featuring more advanced morphological and hemodynamical characteristics.

2023年7月27日 · ROC curve revealed that a 3D VCA ≥ .55 cm 2 is the optimal cutoff point to predict MVPt+ phenotype. Secondary leaflet tethering is a significant mechanism behind severe degenerative MR, resulting in an MVPt+ phenotype featuring more advanced morphological and hemodynamical characteristics. The authors declare no conflicts of interest.

Background The purpose of the study was to determine the association between vena contracta area (VCA) and secondary leaflet tethering among mitral valve prolapse (MVP) patients, and …

本研究的目的是确定二尖瓣脱垂 (MVP) 患者中腔收缩面积 (VCA) 与二次瓣叶栓系之间的关联，从而进一步识别和表征具有病理性瓣叶栓系 (MVPt+) 表型的 MVP。

Results Of the 94 patients with MVP and significant MR, 31 patients showed a TVi > 0.7 ml/m 2 and entered the MVP with leaflet tethering (MVPt+) group. In stepwise multivariate analysis, only prolapse volume index and TVi was independently associated with 3D VCA.

Through-space charge transfer (TSCT) via intramolecular interaction has proved to be one of the most potent techniques employed to achieve 100% internal quantum efficiency. However, …

BackgroundThe purpose of the study was to determine the association between vena contracta area (VCA) and secondary leaflet tethering among mitral valve prolapse (MVP) patients, and thus to further identify and characterize an MVP with pathological leaflet tethering (MVPt+) phenotype.MethodsWe prospectively evaluated 94 consecutive MVP patients with significant mitral regurgitation (MR) and 21 ...

2023年7月27日 · ROC curve revealed that a 3D VCA ≥ .55 cm 2 is the optimal cutoff point to predict MVPt+ phenotype. Secondary leaflet tethering is a significant mechanism behind severe degenerative MR, resulting in an MVPt+ phenotype featuring more advanced morphological and hemodynamical characteristics. The authors declare no conflicts of interest.

MVPt+ group was defined as tenting volume index (TVi) > 0.7 ml/m . The three-dimensional (3D) geometry of mitral valve apparatus and VCA was measured with dedicated quantification software. Results...