Myocardial ischaemia is responsible for angina, unstable angina, and, less commonly, shortness of breath secondary to ischaemic left ventricular dysfunction (angina equivalent) as well as cardiac arrhythmias.

2021年5月5日 · Myocardial ischemia occurs when blood flow to the heart muscle (myocardium) is obstructed by a partial or complete blockage of a coronary artery by a buildup of plaques (atherosclerosis). If the plaques rupture, you can have a heart attack (myocardial infarction).

In our viewpoint, myocardial ischemia is directly dependent on an impairment of the cross talk between myocardial energy state and coronary blood flow. Coronary macrovascular and microvascular disease may represent just a portion of the multifaceted pathophysiology of myocardial ischemia.

2022年5月27日 · Too little blood flow through your coronary artery causes myocardial ischemia. What is myocardial ischemia? Myocardial ischemia (or cardiac ischemia) means your heart muscle is not getting enough blood (which contains oxygen and nutrients) to work as it should.

Myocardial ischaemia is responsible for angina, unstable angina, and, less commonly, shortness of breath secondary to ischaemic left ventricular dysfunction (angina equivalent) as well as cardiac arrhythmias.

2016年6月26日 · We here review the pathophysiology of acute myocardial infarction and reperfusion, notably the temporal and spatial evolution of ischaemic and reperfusion injury, the different modes of cell death, and the resulting coronary microvascular dysfunction.

This review summarizes the current knowledge of the molecular mechanisms underlying myocardial ischemia and discusses new potential therapeutic interventions for reducing acute myocardial ischemic injury and post-ischemic cardiac remodeling. 2. Pathophysiology of Myocardial Infarction

2024年1月12日 · In this review, Heusch summarizes the state of the art in our pathophysiological understanding of myocardial ischemia/reperfusion and outlines where further mechanistic knowledge is needed to facilitate translation to clinical practice.

2024年1月12日 · Myocardial ischemia/reperfusion is the pathophysiological substrate of ischemic heart disease. Improvements in prevention and treatment of ischemic heart disease have reduced mortality in developed count …

Myocardial ischemia is a consequence of reduced blood flow in coronary arteries, due to a combination of fixed vessel narrowing and abnormal vascular tone as a result of atherosclerosis and endothelial dysfunction. This leads to an imbalance …