2020年3月1日 · A major diagnostic application of 18 F-NaF PET scan that has been explored is its use in the detection of osseous lesions of metastatic cancers such as breast, prostate, and lung cancers.

2021年6月1日 · 18F-NaF PET/CT is indicated for diagnostic imaging of bone to define altered osteogenic areas of activity. It provides high-resolution, high-contrast images of the skeletal tissue and has higher sensitivity, specificity, and accuracy than conventional nuclear bone scintigraphy.

Fluorine 18-Fluorodeoxyglucose positron emission tomography/computerized tomography (18F-FDG PET/CT) is now used as a useful imaging tool for staging, restaging and evaluation of therapy response for most cancers.

2020年4月3日 · Fluorine-18-labeled sodium fluoride (also known as 18F-NaF or sodium fluoride) is a PET radiotracer used primarily for skeletal imaging. Fluorine-18-labeled sodium fluoride is an ionic compound comprised of a single sodium atom …

2010年11月1日 · 18 F is a diagnostic molecular imaging agent used for identification of new bone formation. 18 F, administered as intravenous Na 18 F, was approved by the U.S. Food and Drug Administration in 1972 but has been listed as a discontinued drug since 1984.

2018年4月1日 · This paper evaluates the use of18 F-NaF PET/CT scan as possible method to follow the course of a flare-up in FOP. Its findings support previous observations in an FOP patient where, after surgery, repeated18 F-NaF PET/CT scans could identify and quantify early foci of disease activity, which led to heterotopic ossification at a later stage(4) .

Despite the historical legacy and widespread current clinical practice that employs 99m Tc-based bone scintigraphy, the use of positron emission tomography (PET) with 18 F-sodium fluoride (18 F-NaF) is increasing. 18 F-NaF was introduced in 1962 and approved for clinical use by the U.S. Food and Drug Administration in 1972 (2, 3).

2015年7月23日 · The object of the dynamic PET scan is to obtain the time-activity curves (TAC) for the concentration of 18 F-NaF in the bone ROI and arterial blood during the first 60 min following the bolus injection.

18F–sodium fluoride (18F-NaF) PET/CT provides high sensitivity and specificity for the assessment of bone and joint diseases. It is able to accurately differentiate malignant from benign bone lesions, especially when using dynamic quantitative approaches.

2018年4月27日 · NaF PET/CT hybrid fusion imaging is extremely useful in identifying potential causes of pain in patients with malignancies that have an affinity for skeletal metastases. This technique can help detect bone metastases, in problem solving, and to …