This review evaluates current clinical literature on the use of platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP (LP-PRP), in order to develop evidence-based recommendations for various musculoskeletal ...

Platelet-rich plasma (PRP) as a biological agent has gained popularity over the last decade or more in treating a wide variety of conditions in different fields of medicine. PRP is derived from the centrifugation of a patient’s whole blood to produce an increased concentration of autologous platelets in a small volume of plasma [1, 2].

In order to advance PRP in particular (and autologous cellular medicine therapies in general), we have developed these guidelines to assist physicians in performing safe therapies, promote patient education, encourage robust clinical research and begin to define the scope and anticipated effects of these procedures.

Platelet-rich plasma (PRP) activation is emerging as a promising and multifaceted tool for accelerating skin wound healing. This review extensively examines PRP's role in wound healing, focusing on its composition, mechanisms of action, activation methods, and clinical applications.

2024年8月5日 · The review included randomized controlled trials (RCTs) involving human participants undergoing PRP treatment for aesthetic or regenerative purposes. Key parameters such as the PRP preparation methods, platelet concentration, and quality control measures were analyzed. The study protocol was registered with PROSPERO (ID: CRD42024557669).

2019年6月17日 · 富血小板血浆 ( platelet-rich plasma，PRP) 是通 过离心的方法从自体血中提取出来的血小板浓缩 物。 PRP 来源于自体、无免疫排斥、制作简单，临床 应用安全。 研究报道，应 用 PRP 可以促进骨折愈 合，加快创面修复，减少术后并发症，促进术后功能 恢复等[1 － 3]。

2025年2月21日 · Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration.

Introduction: Platelet-rich plasma (PRP) is an autologous blood-derived product that contains platelet concentrations at least 2/3 times above the normal level and includes platelet-related growth factors. The concept of PRP began in the 1970s in the field of hematology to treat patients with thrombocytopenia.

Platelet-rich plasma (PRP) is perhaps the most widely studied of the biologic therapies, with an ever-growing body of evidence supporting its safety and efficacy in decreasing inflammation and pain and promoting healing in the setting of both nonoperative and operative treatments. PRP is …

Platelet-rich plasma (PRP) is a promising treatment for musculoskeletal maladies and clinical data to date have shown that PRP is safe. However, evidence of its efficacy has been mixed and highly variable depending on the specific indication.