2023年4月5日 · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths and substantial morbidity worldwide. Intense scientific effort to understand the biology of...

2022年6月10日 · 10 million sequences of COVID-19’s genomic code have now been organized into a phylogenetic tree in the UC Santa Cruz SARS-CoV-2 Browser, which is the largest tree of genomic sequences of a single species ever assembled.

2020年12月22日 · Here we applied the matrix representation with parsimony (MRP) pseudo-sequence supertree analysis to study the origin and evolution of SARS-CoV-2. Compared with other phylogenetic analysis...

Based on phylogenetic inferences, sequence analysis and structure–function relationships of coronavirus proteins, informed by the knowledge currently available on the virus, we discuss the different scenarios on the origin—natural or synthetic—of the virus.

Scientists around the world use powerful technologies to quickly find mutations in samples from COVID-19 patients. The Nextstrain team uses that data to build viral “family trees,” which let them trace the virus’s travels around the globe. Next to the Nextstrain map is a phylogenetic tree.

2022年8月11日 · In a 1.6 million sample tree from May 2021, we identify 589 recombination events, which indicate that around 2.7% of sequenced SARS-CoV-2 genomes have detectable recombinant ancestry.

2020年4月6日 · Scientists can study the evolution of SARS-CoV-2 to learn more about how the genes of the virus function. It is also useful to make inferences about the spread of the virus around the world,...

Coronaviridae, in turn, are members of the order Nidovirales, a group of enveloped, positive-stranded RNA viruses. Here we present a systematic phylogenetic and evolutionary study based on protein domain architecture, encompassing the entire proteomes of all Orthocoronavirinae, as well as other Nidovirales.

2021年3月22日 · Research has shown that furin cleavage sites have naturally occurred many times in coronavirus evolution. The origin of SARS-CoV-2 is considered to be bat-borne due to the close genetic...

2020年12月10日 · We used genomic epidemiology to investigate the introduction and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area across the first wave of the pandemic, from March through May 2020, including high-density sampling early in …